ArticleeLife2021
The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci.
Abstract read
In one paragraph
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Analysing pneumococcal invasiveness using Bayesian models of pathogen progression rates.PLoS computational biology · 2022Pooled it
- Artificial Intelligence-Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Epistasis and co-adaptation in bacterial genome evolution.Nature reviews. Genetics · 2026Review
- Genomic epidemiology ofMicrobial genomics · 2026Article
- Genomic characterization of mobile genetic elements associated with antimicrobial resistance inMicrobial genomics · 2026Article
- A mini review of genome-predicted β-lactam susceptibility inFrontiers in cellular and infection microbiology · 2026Review
- Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy.Nature communications · 2025Article
- Two Independent Acquisitions of Multidrug Resistance Gene lsaC in Streptococcus pneumoniae Serotype 20 Multilocus Sequence Type 1257.Emerging infectious diseases · 2025Article
- Chromosomal Curing Drives an Arms Race Between Bacterial Transformation and Prophage.Molecular biology and evolution · 2025Article
- Review
- Pore-C sequencing identifies episome-driven chromosome conformation perturbations differentiating pneumococcal epigenetic variants.PLoS pathogens · 2025Article
- Genomics for antimicrobial resistance-progress and future directions.Antimicrobial agents and chemotherapy · 2025Review
- Optimizing nanopore adaptive sampling for pneumococcal serotype surveillance in complex samples using the graph-based GNASTy algorithm.Genome research · 2025Article
- Comparison of gene-by-gene and genome-wide short nucleotide sequence-based approaches to define the global population structure ofMicrobial genomics · 2024Article
- Detecting co-selection through excess linkage disequilibrium in bacterial genomes.NAR genomics and bioinformatics · 2024Article
- Convergent impact of vaccination and antibiotic pressures on pneumococcal populations.Cell chemical biology · 2024Review
- Genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci.Nature communications · 2024Article
- Diverse regulatory pathways modulate bet hedging of competence induction in epigenetically-differentiated phase variants of Streptococcus pneumoniae.Nucleic acids research · 2023Article
- Loss of Pde1 function acts as an evolutionary gateway to penicillin resistance inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Accurate and fast graph-based pangenome annotation and clustering with ggCaller.Genome research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Joshua C D'AethMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.ORCID 0000-0002-9636-9886
Mark Pg van der LindenInstitute for Medical Microbiology, National Reference Center for Streptococci, University Hospital RWTH Aachen, Aachen, Germany.
Lesley McGeeRespiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, United States.
Herminia de LencastreLaboratory of Molecular Genetics, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.
Paul TurnerCambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, Cambodia.ORCID 0000-0002-1013-7815
Jae-Hoon SongDepartment of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.
Stephanie W LoParasites & Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Rebecca A GladstoneParasites & Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Raquel Sá-LeãoLaboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.
Kwan Soo KoDepartment of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.ORCID 0000-0002-0978-1937
William P HanageCenter for Communicable Disease Dynamics, Harvard T.H. Chan School of Public Health, Boston, United States.
Robert F BreimanDepartment of Global Health, Rollins School of Public Health, Emory University, Atlanta, United States.
Bernard BeallRespiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, United States.
Stephen D BentleyParasites & Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, United Kingdom.
Nicholas J CroucherMRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.ORCID 0000-0001-6303-8768
GPS Consortium
Funding
Ecological and genetic contributions to the spread of resistance in pneumococcusR01AI106786 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI HANAGE, WILLIAM · 2013 to 2017
$3.1MMedical Research Council MR/R015600/1Medical Research Council MR/T016434/1NIAID NIH HHS R01 AI106786Wellcome Trust 098051Wellcome Trust 102169/Z/13/ZWellcome Trust 104169/Z/14/AWellcome Trust 106698Wellcome Trust 206194
Abstract
Multidrug-resistant
Indexed as
Gene Transfer, HorizontalAnti-Bacterial AgentsDNA Transposable ElementsDrug Resistance, BacterialGenes, BacterialGermanyHumansMacrolidesPhylogenyPneumococcal VaccinesSerogroupSerotypingStreptococcus pneumoniaeAnti-Bacterial AgentsDNA Transposable ElementsMacrolidesPneumococcal VaccinesAMRepidemiologygeneticsgenomicsinfectious diseasemicrobiologyrecombinationstreptococcus pneumoniae
Identifiers
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.