Evidence map›Paper›PMID 34259550›Full record

ArticleMicrobiology spectrum2021

Caerin 1.1 and 1.9 Peptides from Australian Tree Frog Inhibit Antibiotic-Resistant Bacteria Growth in a Murine Skin Infection Model.

Shu Chen, Pingping Zhang, Liyin Xiao, Ying Liu, Kuihai Wu, Guoying Ni, Hejie Li, Tianfang Wang, Xiaolian Wu, Guoqiang Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Caerin 1.1/1.9 peptides controlFrontiers in microbiology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Going Beyond Host Defence Peptides: Horizons of Chemically Engineered Peptides for Multidrug-Resistant Bacteria.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Shu Chen *Cancer Research Institute, Foshan First People's Hospital, Foshan, Guangdong, China.
Pingping Zhang *Cancer Research Institute, Foshan First People's Hospital, Foshan, Guangdong, China.
Liyin XiaoCancer Research Institute, Foshan First People's Hospital, Foshan, Guangdong, China.
Ying LiuCancer Research Institute, Foshan First People's Hospital, Foshan, Guangdong, China.
Kuihai WuClinical Microbiological Laboratory, Foshan First People's Hospital, Foshan, Guangdong, China.
Guoying NiGenecology Research Centre, University of the Sunshine Coastgrid.1034.6, Maroochydore, QLD, Australia.
Hejie LiGenecology Research Centre, University of the Sunshine Coastgrid.1034.6, Maroochydore, QLD, Australia.
Tianfang WangGenecology Research Centre, University of the Sunshine Coastgrid.1034.6, Maroochydore, QLD, Australia.
Xiaolian WuCancer Research Institute, Foshan First People's Hospital, Foshan, Guangdong, China.
Guoqiang ChenDepartment of Rheumatology, Foshan Frist People's Hospital, Foshan, Guangdong, China.
Xiaosong LiuCancer Research Institute, Foshan First People's Hospital, Foshan, Guangdong, China.ORCID 0000-0001-9577-7725
First People's Hospital of Foshan · CNUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The host defense peptide caerin 1.9 was originally isolated from skin secretions of an Australian tree frog and inhibits the growth of a wide range of bacteria

Indexed as

Drug Resistance, BacterialAcinetobacter baumanniiAmphibian ProteinsAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAnuraAustraliaBacterial InfectionsFemaleHumansMethicillin-Resistant Staphylococcus aureusMiceMice, Inbred BALB CMice, Inbred C57BLMicrobial Sensitivity TestsAmphibian ProteinsAnti-Bacterial AgentsAntimicrobial Cationic Peptidescaerin 1.1, Anuracaerin 1.9 protein, Litoriaanimal modelantibacterialcaerin peptidesMRSAnatural antimicrobial agentskin infectionsoft tissue infection

Identifiers

PMID34259550
PMCPMC8552723
OpenAlexW3178472217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.