Evidence map›Paper›PMID 34259391›Full record

ArticleJournal of the International AIDS Society2021

Annual home-based HIV testing in the Chókwè Health Demographic Surveillance System, Mozambique, 2014 to 2019: serial population-based survey evaluation.

Duncan MacKellar, Ricardo Thompson, Robert Nelson, Isabelle Casavant, Sherri Pals, Juvencio Bonzela, Alicia Jaramillo, Judite Cardoso, Dawud Ujamaa, Stelio Tamele and 7 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Duncan MacKellarDivision of Global HIV and TB, National Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0001-8217-9881
Ricardo ThompsonChókwè Health Research and Training Center, National Institute of Health, Chókwè, Mozambique.
Robert NelsonDivision of Global HIV and TB, National Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Isabelle CasavantUS Centers for Disease Control and Prevention, Maputo, Mozambique.
Sherri PalsDivision of Global HIV and TB, National Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Juvencio BonzelaChókwè Health Research and Training Center, National Institute of Health, Chókwè, Mozambique.
Alicia JaramilloJhpiego at Johns Hopkins University, Maputo, Mozambique.
Judite CardosoJhpiego at Johns Hopkins University, Maputo, Mozambique.
Dawud UjamaaICF International, Atlanta, GA, USA.
Stelio TameleDistrict Directorate of Public Health, Chókwè, Mozambique.
Victor ChivurreProvincial Directorate of Public Health, Xai-Xai, Mozambique.
Inacio MalimaneUS Centers for Disease Control and Prevention, Maputo, Mozambique.
Ishani PathmanathanDivision of Global HIV and TB, National Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Kristen HeitzingerUS Centers for Disease Control and Prevention, Maputo, Mozambique.
Stanley WeiUS Centers for Disease Control and Prevention, Maputo, Mozambique.
Aleny CoutoMozambique Ministry of Health, Maputo, Mozambique.
Alfredo VergaraUS Centers for Disease Control and Prevention, Maputo, Mozambique.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWHO recommends implementing a mix of community and facility testing strategies to diagnose 95% of persons living with HIV (PLHIV). In Mozambique, a country with an estimated 506,000 undiagnosed PLHIV, use of home-based HIV testing services (HBHTS) to help achieve the 95% target has not been evaluated.

methodsHBHTS was provided at 20,000 households in the Chókwè Health Demographic Surveillance System (CHDSS), Mozambique, in annual rounds (R) during 2014 to 2019. Trends in prevalence of HIV infection, prior HIV diagnosis among PLHIV (diagnostic coverage), and undiagnosed HIV infection were assessed with three population-based surveys conducted in R1 (04/2014 to 04/2015), R3 (03/2016 to 12/2016), and R5 (04/2018 to 03/2019) of residents aged 15 to 59 years. Counts of patients aged ≥15 years tested for HIV in CHDSS healthcare facilities were obtained from routine reports.

resultsDuring 2014 to 2019, counsellors conducted 92,512 home-based HIV tests and newly diagnosed 3711 residents aged 15 to 59 years. Prevalence of HIV infection was stable (R1, 25.1%; R3 23.6%; R5 22.9%; p-value, 0.19). After the first two rounds (44,825 home-based tests; 31,717 facility-based tests), diagnostic coverage increased from 73.8% (95% CI 70.3 to 77.2) in R1 to 93.0% (95% CI 91.3 to 94.7) in R3, and prevalence of undiagnosed HIV infection decreased from 6.6% (95% CI 5.6 to 7.5) in R1 to 1.7% (95% CI 1.2 to 2.1) in R3. After two more rounds (32,226 home-based tests; 46,003 facility-based tests), diagnostic coverage was 95.4% (95% CI 93.7 to 97.1) and prevalence of undiagnosed HIV infection was 1.1% (95% CI 0.7 to 1.5) in R5. Prevalence of having last tested at home was 12.7% (95% CI 11.3 to 14.0) in R1, 45.2% (95% CI 43.4 to 47.0) in R3, and 41.4% (95% CI 39.5 to 43.2) in R5, and prevalence of having last tested at a healthcare facility was 45.3% (95% CI 43.3 to 47.3) in R1, 40.1% (95% CI 38.4 to 41.8) in R3, and 45.2% (95% CI 43.3 to 47.0) in R5.

conclusionsHBHTS successfully augmented facility-based testing to achieve HIV diagnostic coverage in a high-burden community of Mozambique. HBHTS should be considered in sub-Saharan Africa communities striving to diagnose 95% of persons living with HIV.

Indexed as

HIV InfectionsGovernment ProgramsHIV TestingHumansMozambiquePrevalenceHIV diagnostic coveragehome-based HIV testing and counsellingMozambiqueprevalence of undiagnosed HIV infection

Identifiers

PMID34259391
PMCPMC8278856

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.