ArticleSeminars in dialysis2021
Outcomes of symptomatic coronavirus disease 19 in maintenance hemodialysis patient in India.
Article in Seminars in dialysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for mortality in hemodialysis patients with COVID-19: a systematic review and meta-analysis.Renal failure · 2021Pooled it
- Outcomes of symptomatic coronavirus disease 19 in maintenance hemodialysis patient in India.Seminars in dialysis · 2021Article
- Brazilian Dialysis Survey 2020.Jornal brasileiro de nefrologiaArticle
- Brazilian Dialysis Survey 2021.Jornal brasileiro de nefrologiaArticle
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17 authors.
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Abstract
backgroundMaintenance hemodialysis (MHD) patients face disadvantages with higher risk of acquiring SARS-CoV-2 infection, atypical manifestations, and associated multiple comorbidities. We describe patients' outcomes with symptomatic COVID-19 on MHD in a large cohort of patients from India.
methodsData were collected prospectively from hemodialysis units in 11 public and private hospitals between March 15, 2020, and July 31, 2020. The survival determinants were analyzed using stepwise backward elimination cox-regression analysis.
resultsOf the 263 total patients (mean age 51.76 ± 13.63 years and males 173) on MHD with symptomatic COVID-19, 35 (13.3%) died. Those who died were older (p = 0.01), had higher frequency of diabetic kidney disease (p = 0.001), comorbidities (p = 0.04), and severe COVID-19 (p = 0.001). Mortality was higher among patients on twice-weekly MHD than thrice-weekly (p = 0.001) and dialysis through central venous catheter (CVC) as compared to arteriovenous fistula (p = 0.001). On multivariate analysis, CVC use (HR 2.53, 95% CI 1.26-5.07, p = 0.009), disease severity (HR = 3.54, 95% CI 1.52-8.26, p = 0.003), and noninvasive ventilatory support (HR 0.59, 95% CI 0.25-0.99, p = 0.049) had significant effect on mortality.
conclusionThe adjusted mortality risk of COVID-19 in MHD patients is high in patients associated with severe COVID-19 and patients having CVC as vascular access.
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