Evidence map›Paper›PMID 34258797›Full record

ReviewEuropean journal of haematology2021

The hemostatic and thrombotic complications of liver disease.

Hannah Stowe McMurry, Janice Jou, Joseph Shatzel

Open access · greenAbstract readReview
In one paragraph

Review in European journal of haematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 31 citations in OpenAlex.

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  15. Hematological abnormalities in liver cirrhosis.World journal of hepatology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hannah Stowe McMurryDivison of Internal Medicine, Oregon Health & Science University, Portland, OR, USA.ORCID https://orcid.org/0000-0002-5596-1285
Janice JouDivision of Gastroenterology and Hepatology, Oregon Health & Science University, Portland, OR, USA.
Joseph ShatzelDivision of Hematology and Oncology, Oregon Health & Science University, Portland, OR, USA.ORCID https://orcid.org/0000-0001-9396-5976
Oregon Health & Science University · US

Funding

Evaluating the Safety and Efficacy of Targeting the Contact Pathway to Prevent Device Associated Thrombosis.R01HL151367 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHATZEL, JOSEPH JAMES · 2020 to 2024
$1.5M
NHLBI NIH HHS R01 HL151367
6 · The paper itself

Abstract

Hepatic cirrhosis leads to numerous hematologic derangements resulting in a complex and tenuously rebalanced hemostatic milieu. The utility of common hematologic tests including the INR and aPTT in assessing hemostatic and thrombotic risk in patients with cirrhosis is limited, and consensus on transfusion thresholds and proper management of thrombotic complications continues to evolve. This review summarizes the pathophysiology of key derangements of hemostasis including those of platelets, von Willebrand factor, pro- and anticoagulation factors, and fibrin. Additionally, the pathogenesis, consequences, optimal management, and prevention of major thrombotic and bleeding complications in cirrhosis arte discussed.

Indexed as

AnticoagulantsBlood PlateletsBlood TransfusionFibrinogenHemostasisHeparin, Low-Molecular-WeightHumansLiver CirrhosisThrombosisvon Willebrand FactorAnticoagulantsFibrinogenHeparin, Low-Molecular-Weightvon Willebrand Factorblood coagulationhemostasishumansliver cirrhosisthrombosis

Identifiers

PMID34258797
PMCPMC9009189
OpenAlexW3179292870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.