Evidence map›Paper›PMID 34258534›Full record

ArticleIJU case reports2021

Nonmetastatic castration-resistant prostate cancer treated with salvage focal brachytherapy after external beam radiotherapy.

Soichiro Yoshida, Yoh Matsuoka, Kazuma Toda, Sho Uehara, Hajime Tanaka, Minato Yokoyama, Kazutaka Saito, Ryoichi Yoshimura, Yasuhisa Fujii

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Soichiro YoshidaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Yoh MatsuokaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Kazuma TodaDepartment of Radiation Therapeutics and Oncology Tokyo Medical and Dental University Tokyo Japan.
Sho UeharaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Hajime TanakaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.ORCID https://orcid.org/0000-0003-3632-2901
Minato YokoyamaDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Kazutaka SaitoDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Ryoichi YoshimuraDepartment of Radiation Therapeutics and Oncology Tokyo Medical and Dental University Tokyo Japan.
Yasuhisa FujiiDepartment of Urology Tokyo Medical and Dental University Tokyo Japan.
Tokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe efficacy of salvage local therapy after external beam radiotherapy has recently gained attention. However, a challenge with these therapies is the risk of significant genitourinary and gastrointestinal toxicity. Focal brachytherapy may be a treatment option because of its potential to reduce side effects. CASE PRESENTATION: A patient with castration-resistant prostate cancer was found to be free of metastases on whole-body magnetic resonance imaging following external beam radiotherapy, and prostate biopsy revealed a localized recurrence in the ventral prostate. The patient underwent salvage focal brachytherapy and had a prostate-specific antigen progression-free survival of 23 months. No adverse effects were observed following salvage brachytherapy.

conclusionOur case suggests that salvage focal brachytherapy may be an effective local treatment option for nonmetastatic castration-resistant prostate cancer that has relapsed after external beam radiotherapy, wherein the lesion is confined to a small area within the prostate.

Indexed as

brachytherapycastration‐resistanthemi‐gland focal therapyprostatic neoplasmsradiotherapysalvage therapy

Identifiers

PMID34258534
PMCPMC8255295
OpenAlexW3159943067

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.