Evidence map›Paper›PMID 34258530›Full record

ArticleIJU case reports2021

Prominent response to platinum-based chemotherapy in a patient with

Tatsuaki Daimon, Takeo Kosaka, Hiroshi Hongo, Eriko Aimono, Kohei Nakamura, Shuji Mikami, Hiroshi Nishihara, Mototsugu Oya

Open access · goldAbstract readCase Reports
In one paragraph

Article in IJU case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tatsuaki DaimonDepartment of Urology Keio University School of Medicine Tokyo Japan.
Takeo KosakaDepartment of Urology Keio University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-4371-4594
Hiroshi HongoDepartment of Urology Keio University School of Medicine Tokyo Japan.
Eriko AimonoGenomics Unit Keio Cancer Center Keio University School of Medicine Tokyo Japan.
Kohei NakamuraGenomics Unit Keio Cancer Center Keio University School of Medicine Tokyo Japan.
Shuji MikamiDivision of Diagnostic Pathology Keio University Hospital Tokyo Japan.
Hiroshi NishiharaGenomics Unit Keio Cancer Center Keio University School of Medicine Tokyo Japan.
Mototsugu OyaDepartment of Urology Keio University School of Medicine Tokyo Japan.
Keio University · JPKeio University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGenomic profiling provides useful information for diagnosis, treatment, and prognosis, and detection of certain defects, such as DNA repair gene aberrations or microsatellite instability, can possibly lead to optimal treatment, but this testing has not been widely used to inform prostate cancer treatment. CASE PRESENTATION: A 55-year-old man sequentially treated for prostate cancer was diagnosed as neuroendocrine prostate cancer from prostate specimens resected because of urinary retention. Subsequently, he received five cycles of platinum-based chemotherapy in total and responded well. We also performed next-generation sequencing of a sample from the prostate specimen and identified a

conclusionWe report a neuroendocrine prostate cancer patient with

Indexed as

BRCA2genomic profilingMDM2neuroendocrine prostate cancer

Identifiers

PMID34258530
PMCPMC8255288
OpenAlexW3158474867

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.