Evidence map›Paper›PMID 34258493›Full record

ArticleJournal of the Endocrine Society2021

Physical and Reported Subjective Health Status in 222 Individuals with XY Disorder of Sex Development.

Xin Li Gong, Klemens Raile, Jolanta Slowikowska-Hilczer, Catherine Pienkowski, Marcus Quinkler, Robert Roehle, Anna Nordenström, Uta Neumann

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Endocrine Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Xin Li GongCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Pediatric Endocrinology and Diabetology, Berlin, Germany.
Klemens RaileCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Pediatric Endocrinology and Diabetology, Berlin, Germany.
Jolanta Slowikowska-HilczerDepartment of Andrology and Reproductive Endocrinology, Medical University of Lodz, Lodz, Poland.
Catherine PienkowskiReference Center for Rare Gynecological Pathologies, Pediatric Endocrinology Unit, Children's Hospital, CHU Toulouse, France.
Marcus QuinklerEndocrinology in Charlottenburg, Berlin, Germany.ORCID https://orcid.org/0000-0003-4028-1671
Robert RoehleCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Biometry and Clinical Epidemiology, Coordinating Center for Clinical Studies, Berlin, Germany.
Anna NordenströmWomen´s and Children´s Health, Karolinska Institutet, Stockholm, Sweden.
Uta NeumannCharité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Center for chronic sick children, Department of Pediatric Endocrinology, Berlin, Germany.ORCID https://orcid.org/0000-0003-3892-0577
Humboldt-Universität zu Berlin · DEKarolinska Institutet · SEMedical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextLittle is known about the physical health of individuals with 46,XY disorders of sex development (DSD).

objectiveTo assess physical and reported subjective health of individuals with XY DSD.

methodsAs part of the dsd-LIFE study, patients with an XY DSD condition were analyzed in different diagnosis groups for metabolic parameters, comorbidities, metabolic syndrome, bone outcomes, and reported subjective health. Findings were evaluated by descriptive statistics.

resultsA total of 222 patients with XY DSD were included with a mean age of 28.8 ± 12.2 years, mean height of 175.3 ± 7.7 cm, mean weight of 74.3 ± 20.0 kg, and mean body mass index of 24.1 ± 6.0 kg/m

conclusionParticipants reported a lower subjective health status than Eurostat data but their overall metabolic health status was good. Decreased BMD at lumbar spine was especially present in gonadectomized individuals with CAIS and no estrogen therapy.

Indexed as

bone healthcomorbiditiesmetabolismphysical and subjective healthXY DSD

Identifiers

PMID34258493
PMCPMC8271184
OpenAlexW3169819143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.