Evidence map›Paper›PMID 34258484›Full record

ArticleCell surface (Amsterdam, Netherlands)2021

Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen

Guisheng Zeng, Xiaoli Xu, Jiaxin Gao, Alessandra da Silva Dantas, Neil A R Gow, Yue Wang

Open access · goldAbstract read
In one paragraph

Article in Cell surface (Amsterdam, Netherlands), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Application of the Mutant Libraries forInternational journal of molecular sciences · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Guisheng ZengInstitute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.
Xiaoli XuInstitute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.
Jiaxin GaoInstitute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.
Alessandra da Silva DantasMRC Centre for Medical Mycology, School of Biosciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
Neil A R GowMRC Centre for Medical Mycology, School of Biosciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK.
Yue WangInstitute of Molecular and Cell Biology, 61 Biopolis Drive, Proteos, Singapore 138673, Singapore.
Institute of Molecular and Cell Biology · SGUniversity of Exeter · GBNational University of Singapore · SG

Funding

Wellcome Trust
6 · The paper itself

Abstract

Understanding the molecular mechanisms governing antifungal resistance is crucial for identifying new cellular targets for developing new antifungal therapeutics. In this study, we performed a transposon-mediated genome-wide genetic screen in haploid

Indexed as

Antifungal resistanceCaspofunginCell wallChitin synthesisFungal pathogens

Identifiers

PMID34258484
PMCPMC8254124
OpenAlexW3177324998

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.