Evidence map›Paper›PMID 34258478›Full record

ArticleBioactive materials2021

Dual stimuli-responsive polyurethane-based hydrogels as smart drug delivery carriers for the advanced treatment of chronic skin wounds.

Rossella Laurano, Monica Boffito, Michela Abrami, Mario Grassi, Alice Zoso, Valeria Chiono, Gianluca Ciardelli

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 63 citations in OpenAlex.

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  19. Regulated extravascular microenvironmentBioactive materials · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rossella LauranoPolitecnico di Torino, Mechanical and Aerospace Engineering Department, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Monica BoffitoPolitecnico di Torino, Mechanical and Aerospace Engineering Department, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Michela AbramiUniversità degli Studi di Trieste, Department of Engineering and Architecture, Via Alfonso Valerio 6/1, 34127, Trieste, Italy.
Mario GrassiUniversità degli Studi di Trieste, Department of Engineering and Architecture, Via Alfonso Valerio 6/1, 34127, Trieste, Italy.
Alice ZosoPolitecnico di Torino, Mechanical and Aerospace Engineering Department, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Valeria ChionoPolitecnico di Torino, Mechanical and Aerospace Engineering Department, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Gianluca CiardelliPolitecnico di Torino, Mechanical and Aerospace Engineering Department, Corso Duca degli Abruzzi 24, 10129, Torino, Italy.
Politecnico di Torino · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The design of multi-stimuli-responsive vehicles for the controlled and localized release of drugs is a challenging issue increasingly catching the attention of many research groups working on the advanced treatment of hard-to-close wounds. In this work, a thermo- and pH-responsive hydrogel (P-CHP407) was prepared from an

Indexed as

Advanced wound treatmentDrug delivery systemLF-NMR characterizationpH-triggered releasePolyurethane hydrogelStimuli-responsive hydrogel

Identifiers

PMID34258478
PMCPMC8233160
OpenAlexW3129516415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.