Evidence map›Paper›PMID 34258413›Full record

ArticleeNeurologicalSci2021

A case of reversible cerebral vasoconstriction syndrome associated with anti-phospholipid antibody syndrome and systemic lupus erythematosus.

Atsushi Shima, Takakuni Maki, Naoya Mimura, Hirofumi Yamashita, Noriaki Emoto, Hajime Yoshifuji, Ryosuke Takahashi

Open access · goldAbstract readCase Reports
In one paragraph

Article in eNeurologicalSci, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  4. Article
  5. Reversible cerebral vasoconstriction syndrome: literature review.The Egyptian journal of neurology, psychiatry and neurosurgery · 2023
    Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Atsushi ShimaDepartment of Neurology, Kyoto University Graduate School of Medicine, Japan.
Takakuni MakiDepartment of Neurology, Kyoto University Graduate School of Medicine, Japan.
Naoya MimuraDepartment of Neurology, Kyoto University Graduate School of Medicine, Japan.
Hirofumi YamashitaDepartment of Neurology, Kyoto University Graduate School of Medicine, Japan.
Noriaki EmotoLaboratory of Clinical Pharmaceutical Science, Kobe Pharmaceutical University, Japan.
Hajime YoshifujiDepartment of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Japan.
Ryosuke TakahashiDepartment of Neurology, Kyoto University Graduate School of Medicine, Japan.
Kyoto University · JPKobe Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathomechanisms and treatment strategy for rare presentations of reversible cerebral vasoconstriction syndrome (RCVS) with anti-phospholipid syndrome (APS) remain to be determined. We report a 67-year-old woman with APS who presented with ischemic stroke due to RCVS. She was treated with low-dose cilostazol and lomerizine hydrochloride, which resulted in functional improvement and recovery of vasoconstriction within 12 weeks. Her plasma endothelin-1 level was decreased after relief of vasoconstriction, compared with the pre-treatment condition. Increased plasma endothelin-1 may be related to the underlying pathomechanism of RCVS with APS, against which cilostazol and lomerizine hydrochloride could be effective.

Indexed as

Anti-phospholipid antibody syndromeCilostazolEndothelin-1LomerizineReversible cerebral vasoconstriction syndrome

Identifiers

PMID34258413
PMCPMC8253938
OpenAlexW3169796471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.