ArticleStructural dynamics (Melville, N.Y.)2021
Laboratory diffracted x-ray blinking to monitor picometer motions of protein molecules and application to crystalline materials.
Article in Structural dynamics (Melville, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed.
- From Static Structures to Molecular Dynamics: Emerging Directions in X-Ray and Electron Materials Characterization.Materials (Basel, Switzerland) · 2026Review
- Diffracted X-ray blinking reveals signature crystal polymorph dynamics in 1,2,3,5-Tetrabromobenzene.Scientific reports · 2025Article
- Real-Time Observation of Polymer Fluctuations During Phase Transition Using Transmission Electron Microscope.Polymers · 2025Article
- The Blinking of Small-Angle X-ray Scattering Reveals the Degradation Process of Protein Crystals at Microsecond Timescale.International journal of molecular sciences · 2023Article
- Diffracted X-ray Tracking for Observing the Internal Motions of Individual Protein Molecules and Its Extended Methodologies.International journal of molecular sciences · 2023Review
- Diffracted X-ray Tracking Method for Measuring Intramolecular Dynamics of Membrane Proteins.International journal of molecular sciences · 2022Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, real-time observations of molecules have been required to understand their behavior and function. To date, we have reported two different time-resolved observation methods: diffracted x-ray tracking and diffracted x-ray blinking (DXB). The former monitors the motion of diffracted spots derived from nanocrystals labeled onto target molecules, and the latter measures the fluctuation of the diffraction intensity that is highly correlated with the target molecular motion. However, these reports use a synchrotron x-ray source because of its high average flux, resulting in a high time resolution. Here, we used a laboratory x-ray source and DXB to measure the internal molecular dynamics of three different systems. The samples studied were bovine serum albumin (BSA) pinned onto a substrate, antifreeze protein (AFP) crystallized as a single crystal, and poly{2-(perfluorooctyl)ethyl acrylate} (PC
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Registered trials
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