ArticleOpen forum infectious diseases2021
Visceral Adiposity and Severe COVID-19 Disease: Application of an Artificial Intelligence Algorithm to Improve Clinical Risk Prediction.
Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Prevalence and clinical implications of abnormal body composition phenotypes in patients with COVID-19: a systematic review.The American journal of clinical nutrition · 2023Pooled it
- Article
- Association of excess visceral fat and severe illness in hospitalized COVID-19 patients in Japan: a retrospective cohort study.International journal of obesity (2005) · 2024Article
- The role of diet and nutrition in the management of COPD.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Review
- Anthropometric Measurements and Admission Parameters as Predictors of Acute Respiratory Distress Syndrome in Hospitalized COVID-19 Patients.Biomedicines · 2023Article
- Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19. A multicenter study.The British journal of radiology · 2023Article
- Assessment of body composition in adults hospitalized with acute COVID-19: a scoping review.Frontiers in nutrition · 2023Article
- Computed Tomography-Defined Body Composition as Prognostic Parameter in Acute Mesenteric Ischemia.Digestive surgery · 2023Article
- Role of visceral fat areas defined by thoracic CT in acute pulmonary embolism.The British journal of radiology · 2022Article
- Association of Nonalcoholic Fatty Liver Disease With COVID-19 Severity and Pulmonary Thrombosis: CovidFAT, a Prospective, Observational Cohort Study.Open forum infectious diseases · 2022Article
- Whole-Body MRI-Derived Adipose Tissue Characterization and Relationship to Pulmonary Function Impairment.Tomography (Ann Arbor, Mich.) · 2022Article
- The Role of Bioelectrical Impedance Analysis in Predicting COVID-19 Outcome.Frontiers in nutrition · 2022Article
- Visceral adipose tissue and risk of COVID-19 susceptibility, hospitalization, and severity: A Mendelian randomization study.Frontiers in public health · 2022Article
- Overweight and Obesity Are Associated With Acute Kidney Injury and Acute Respiratory Distress Syndrome, but Not With Increased Mortality in Hospitalized COVID-19 Patients: A Retrospective Cohort Study.Frontiers in endocrinology · 2021Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundObesity has been linked to severe clinical outcomes among people who are hospitalized with coronavirus disease 2019 (COVID-19). We tested the hypothesis that visceral adipose tissue (VAT) is associated with severe outcomes in patients hospitalized with COVID-19, independent of body mass index (BMI).
methodsWe analyzed data from the Massachusetts General Hospital COVID-19 Data Registry, which included patients admitted with polymerase chain reaction-confirmed severe acute respiratory syndrome coronavirus 2 infection from March 11 to May 4, 2020. We used a validated, fully automated artificial intelligence (AI) algorithm to quantify VAT from computed tomography (CT) scans during or before the hospital admission. VAT quantification took an average of 2 ± 0.5 seconds per patient. We dichotomized VAT as high and low at a threshold of ≥100 cm
resultsA total of 378 participants had CT imaging. Kaplan-Meier curves showed that participants with high VAT had a greater risk of the outcome compared with those with low VAT (
conclusionsHigh VAT is associated with a greater risk of severe disease or death in COVID-19 and can offer more precise information to risk-stratify individuals beyond BMI. AI offers a promising approach to routinely ascertain VAT and improve clinical risk prediction in COVID-19.
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Registered trials
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