Evidence map›Paper›PMID 34258276›Full record

ArticleBioMed research international2021

Correlations between FTO Gene Polymorphisms and TSH Level in Uyghur Chinese Patients with Type 2 Diabetes.

Li Wang, QiZhong Yi, Hua Yao, LiJuan He, BinBin Fang, WeiFang Xu, YinXia Su, JiWen Liu, Qi Ma

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Li WangKey Laboratory of Xinjiang Metabolic Disease, Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0002-7973-0756
QiZhong YiPsychological Medicine Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0003-2413-9472
Hua YaoKey Laboratory of Xinjiang Metabolic Disease, Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0002-9572-5578
LiJuan HeDepartments of Occupational and Environmental Health, Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0001-6186-3692
BinBin FangClinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0002-9072-5106
WeiFang XuAnesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0003-3401-2504
YinXia SuHealth Management Centre, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0001-7650-9370
JiWen LiuDepartments of Occupational and Environmental Health, Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0002-3798-0714
Qi MaKey Laboratory of Xinjiang Metabolic Disease, Clinical Medical Research Institute, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0001-9925-6492
Xinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the correlation between polymorphisms in the FTO gene and TSH level in Uyghur patients with type 2 diabetes in the Xinjiang region.

resultsThe results suggested the TSH level was 2.281 times higher in rs8050136 CC+CA carriers than in AA genotype (95%CI = 1.024~5.080,

conclusionThe polymorphisms at rs8050136 and rs9939609 are associated with changes in the TSH level with rs8050136 CC and rs9939609 TT genotypes identified as potential risk factors for increased TSH levels in these male patients.

Indexed as

Polymorphism, Single NucleotideAdultAllelesAlpha-Ketoglutarate-Dependent Dioxygenase FTOAsian PeopleBody Mass IndexChinaCohort StudiesDiabetes Mellitus, Type 2FemaleGenetic Predisposition to DiseaseGenotypeGlycated HemoglobinHumansLife StyleMaleAlpha-Ketoglutarate-Dependent Dioxygenase FTOFTO protein, humanGlycated Hemoglobinhemoglobin A1c protein, humanThyrotropin

Identifiers

PMID34258276
PMCPMC8257352
OpenAlexW3176733944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.