Evidence map›Paper›PMID 34258258›Full record

Trial reportBioMed research international2020

Vessel Density and Structural Measurements in Primary Angle-Closure Suspect Glaucoma Using Optical Coherence Tomography Angiography.

Yi Zha, Juanjuan Chen, Shuyu Liu, Jinfei Zhuang, Jianqiu Cai

Open access · hybridAbstract readClinical TrialComparative Study
In one paragraph

Trial report in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. The use of tranexamic acid reduces blood loss in osteotomy at knee level: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Pooled it
  2. Long-term optic nerve head microvascular impairment after acute primary angle closure: an OCTA study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Use of tranexamic acid in medial open wedge high tibial osteotomy.Archives of orthopaedic and trauma surgery · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yi ZhaDepartment of Ophthalmology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.ORCID https://orcid.org/0000-0002-6955-0049
Juanjuan ChenDepartment of Ophthalmology, The First Affiliated Hospital of Jiangxi Medical College, Shangrao, Jiangxi 330000, China.ORCID https://orcid.org/0000-0003-2314-9054
Shuyu LiuDepartment of Ophthalmology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.ORCID https://orcid.org/0000-0001-5860-4462
Jinfei ZhuangDepartment of Ophthalmology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.ORCID https://orcid.org/0000-0001-9025-4677
Jianqiu CaiDepartment of Ophthalmology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.ORCID https://orcid.org/0000-0003-0631-6631
Wenzhou Medical University · CNFirst Affiliated Hospital of Jiangxi Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo measure the macular retinal vessel density (VD) and peripapillary retinal nerve fiber layer (RNFL) in primary angle-closure suspects (PACS) by Angio-OCT to be compared with normal subjects.

methodsPrimary angle-closure suspect patients and normal subjects were enrolled in this study. The demographic and clinical characteristics of all subjects, such as RNFL thickness, retinal vessel density, and ocular perfusion pressure, were compared.

resultsNo significant difference was found in both groups on age, sex distribution, intraocular pressure (IOP), and retinal vessel density. The PACS group exhibited significantly thicker RNFL thickness compared with the control group. The deep vessel density was negatively associated with age (

conclusionsOCTA showed significant thicker change on RNFL in the PACS group. Only OPP was independently associated with RNFL in the PACS group.

Indexed as

Fluorescein AngiographyTomography, Optical CoherenceAgedFemaleGlaucoma, Angle-ClosureHumansMaleMiddle AgedOptic DiskRetinal Vessels

Identifiers

PMID34258258
PMCPMC8243897
OpenAlexW3107670959

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.