ArticlePreventive medicine reports2021
Is there a bidirectional association between sedentary behaviour and cognitive decline in older adults? Findings from the Irish Longitudinal Study on Ageing.
Article in Preventive medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of Different Types of Sedentary Behaviour on Cognitive Function in Older Adults: A Systematic Review.Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals · 2026Pooled it
- Individual sedentary activities and cognitive function in middle-aged and older adults: A systematic review.Journal of Alzheimer's disease : JAD · 2026Pooled it
- Pooled it
- Cross-sectional and longitudinal neural predictors of physical activity and sedentary behaviour from a 6-month randomized controlled trial.Scientific reports · 2024Trial
- Sedentary behavior type matters: compositional analysis of 24-hour movement behaviors and cognitive function in older adults.Journal of activity, sedentary and sleep behaviors · 2026Article
- Cognitive Trajectories and Subsequent Accelerometer-Measured Movement Behavior in Older Adults.JAMA network open · 2026Article
- Physical activity and sedentary behavior patterns in cognitive impairment: findings from a cross-sectional study in Punjab, North India.BMC public health · 2026Article
- Cardiorespiratory fitness and cardiometabolic health are associated with distinct cognitive domains in cognitively healthy older adults.Scientific reports · 2025Article
- The effort hypothesis at the heart of the virtuous circle.EXCLI journal · 2025Review
- Cohort Profile Update: The Harmonised Cognitive Assessment Protocol Sub-study of The Irish Longitudinal Study on Ageing (TILDA-HCAP).International journal of epidemiology · 2024Article
- Historic Cognitive Function Trajectories as Predictors of Sedentary Behavior and Physical Activity in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Sedentary behavior and lifespan brain health.Trends in cognitive sciences · 2024Review
- Replacement of leisure-time sedentary behavior with various physical activities and the risk of dementia incidence and mortality: A prospective cohort study.Journal of sport and health science · 2023Article
- Association of Posttraumatic Stress Disorder With Accelerated Cognitive Decline in Middle-aged Women.JAMA network open · 2022Article
- Associations of Objectively-Measured Sedentary Time and Patterns with Cognitive Function in Non-Demented Japanese Older Adults: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Real-time location systems technology in the care of older adults with cognitive impairment living in residential care: A scoping review.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on whether sedentary behaviour (SB) is related to cognitive decline in older individuals is conflicting, potentially caused by methodological differences in previous studies. To inform public health policies, we analysed both the forward and reverse association across four-years between subjective TV time and objectively-measured SB and four cognitive outcome measures in older adults. The Irish Longitudinal Study on Ageing (TILDA) quantified time spent watching TV using a questionnaire and objective physical activity patterns with a GENEActiv accelerometer. Mixed model analysis examined whether these two measures of SB related to changes in cognitive function (immediate and delayed recall, MMSE, and animal naming task) during a four-year follow-up period. Furthermore, the reverse association between changes in cognition over the preceding four years and SB was investigated. We included 1,276 participants (67 ± 9 years). Longitudinally, every hour of objective SB per day was associated with a -0.01 (95%CI = -0.03;-0.00) lower MMSE score per year. Reversely, a worse decline in immediate and delayed recall over the preceding waves was related to slightly more objective SB (B = -0.24 (95%CI = -0.41;-0.07)) and TV time (B = -0.25 (95%CI = -0.48;-0.03)) at the end of those four years. To conclude, in healthy older individuals, higher levels of objective SB are related to cognitive decline across a four-year follow-up, although the magnitude and clinical relevance are questionable. As preceding cognitive decline is associated with more SB across follow-up, this suggests that a bidirectional association is plausible.
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