Evidence map›Paper›PMID 34258140›Full record

ArticleJIMD reports2021

Translational balancing questioned: Unaltered glycosylation during disulfiram treatment in mannosyl-oligosaccharide alpha-1,2-mannnosidase-congenital disorders of glycosylation (MAN1B1-CDG).

Lisa Kemme, Marianne Grüneberg, Janine Reunert, Stephan Rust, Julien Park, Cordula Westermann, Yoshinao Wada, Oliver Schwartz, Thorsten Marquardt

Open access · goldAbstract read
In one paragraph

Article in JIMD reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Lisa KemmeUniversity Children's Hospital Münster Muenster Germany.ORCID https://orcid.org/0000-0002-8190-6140
Marianne GrünebergUniversity Children's Hospital Münster Muenster Germany.
Janine ReunertUniversity Children's Hospital Münster Muenster Germany.
Stephan RustUniversity Children's Hospital Münster Muenster Germany.
Julien ParkUniversity Children's Hospital Münster Muenster Germany.
Cordula WestermannGerhard-Domagk-Institute of Pathology University Hospital Muenster Muenster Germany.
Yoshinao WadaOsaka Medical Center and Research Institute for Maternal and Child Health Osaka Japan.
Oliver SchwartzUniversity Children's Hospital Münster Muenster Germany.
Thorsten MarquardtUniversity Children's Hospital Münster Muenster Germany.
University Hospital Münster · DEOsaka International Cancer Institute · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MAN1B1-CDG is a multisystem disorder caused by mutations in

Indexed as

disulfiramMAN1B1‐CDG

Identifiers

PMID34258140
PMCPMC8260486
OpenAlexW3138697855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.