Evidence map›Paper›PMID 34258070›Full record

ArticleCase reports in anesthesiology2021

The Use of Methylene Blue during Liver Transplantation for Vasoplegia.

Paul Harding, Thomas Nicholas, Cale Kassel

Abstract readCase Reports
In one paragraph

Article in Case reports in anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paul HardingUniversity of Nebraska Medical Center-College of Medicine, Nebraska Medical Center, Omaha 68198-5520, NE, USA.
Thomas NicholasUniversity of Nebraska Medical Center-Department of Anesthesiology, Nebraska Medical Center, Omaha 68198-7541, NE, USA.ORCID https://orcid.org/0000-0001-7060-6786
Cale KasselUniversity of Nebraska Medical Center-Department of Anesthesiology, Nebraska Medical Center, Omaha 68198-7541, NE, USA.ORCID https://orcid.org/0000-0003-2742-4674

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of methylene blue for vasoplegia in cardiac cases with cardiopulmonary bypass, septic shock, and acute liver failure is well documented. Use of MB for liver transplantation has been largely limited to case reports. We describe three separate liver transplantation patients with significant hypotension following reperfusion. Administration of methylene blue to each patient resulted in a significant decrease in vasopressor medication and two patients weaned completely. We argue that the use of MB should be considered as a treatment option for refractory hypotension.

Identifiers

PMID34258070
PMCPMC8245233

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.