ArticleInternational journal of nephrology2021
The Prevalence and Risk Factors of Hypokalemia in Pregnancy-Related Hospitalizations: A Nationwide Population Study.
Article in International journal of nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Electrolyte homeostasis in pregnancy: from physiological adaptations to clinical disturbances - a nephrologist's perspective.Frontiers in nephrology · 2026Review
- Hypokelemic Periodic Paralysis in Pregnancy-A Rare Case Study.Journal of obstetrics and gynaecology of India · 2025Article
- Hypokalaemia in pregnancy - Prevalence, underlying causes, and an approach to investigation.Obstetric medicine · 2024Article
- Accelerating adverse pregnancy outcomes research amidst rising medication use: parallel retrospective cohort analyses for signal prioritization.BMC medicine · 2024Article
- Association of hypertension in pregnancy with serum electrolyte disorders in late pregnancy among Cameroonian women.Scientific reports · 2023Article
- NMDA Autoimmune Encephalitis and Severe Persistent Hypokalemia in a Pregnant Woman.Brain sciences · 2022Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are no nationwide population studies conducted to analyze the prevalence and risk factors associated with hypokalemia during pregnancy in the U.S.
methodWe retrieved data from the Nationwide Inpatient Sample (NIS) and the National Inpatient Sample of Healthcare Cost and Utilization Project (HCUP) for pregnant patients with hypokalemia from 2012 to 2014. We used a chi-squared test to analyze categorical variables and an adjusted Wald test to compare quantitative variables. We applied logistic regression models to calculate adjusted odds ratios (ORs) with 95% confidence intervals (95% CIs) to identify the risk factors for hypokalemia. We used a
resultAmong 12,431,909 pregnancy-related discharges, females of younger age (mean age 27.0 ± 6.2 vs. 28.1 ± 6.0,
conclusionThe prevalence of hypokalemia during pregnancy was less than 1% in this large, nationwide population-based study. There were significant differences between those patients who developed hypokalemia during pregnancy. Notably, those who had hypokalemia were younger, of African American race, and of a low-income level. Congestive heart failure, coronary artery disease, Cushing's syndrome, GH, and hyperemesis gravidarum were found to be associated with hypokalemia during pregnancy.
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Registered trials
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