Evidence map›Paper›PMID 34258030›Full record

ReviewFuture science OA2021

Current understanding of nonsurgical interventions for refractory differentiated thyroid cancer: a systematic review.

Heidi Jones, Victoria Green, James England, John Greenman

Open access · goldAbstract readReview
In one paragraph

Review in Future science OA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Heidi JonesDepartment of ENT, Hull University Teaching Hospitals NHS Trust, HU16 5JQ, Hull, UK.ORCID https://orcid.org/0000-0002-0361-4337
Victoria GreenDepartment of Biomedical Sciences, Faculty of Health Sciences, University of Hull, HU6 7RX, Hull, UK.ORCID https://orcid.org/0000-0002-0770-2967
James EnglandDepartment of ENT, Hull University Teaching Hospitals NHS Trust, HU16 5JQ, Hull, UK.
John GreenmanDepartment of Biomedical Sciences, Faculty of Health Sciences, University of Hull, HU6 7RX, Hull, UK.ORCID https://orcid.org/0000-0002-6003-6051
University of Hull · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer incidence and related mortality is increasing year-on-year, and although treatment for early disease with surgery and radioiodine results in a 98% 5-year survival rate, recurrence and treatment refractory disease is evident in an unacceptable number of patients. Alternative treatment regimens have therefore been sought in the form of tyrosine kinase inhibitors, immunotherapy, vaccines, chimeric antigen receptor T-cell therapy and oncolytic viruses. The current review aims to consolidate knowledge and highlight the latest clinical trials using secondary therapies in thyroid cancer treatment, focusing on both

Indexed as

chimeric antigen receptor T-cell therapyimmunotherapyoncolytic virusessecondary therapythyroid cancertyrosine kinase inhibitors

Identifiers

PMID34258030
PMCPMC8256328
OpenAlexW3171211118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.