Evidence map›Paper›PMID 34258014›Full record

ArticleIUCrJ2021

Fixed-target serial femtosecond crystallography using

J Mia Lahey-Rudolph, Robert Schönherr, Miriam Barthelmess, Pontus Fischer, Carolin Seuring, Armin Wagner, Alke Meents, Lars Redecke

Open access · goldAbstract read
In one paragraph

Article in IUCrJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Chemical reviews · 2026
    Review
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  9. Review
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  12. Serial femtosecond crystallography.Nature reviews. Methods primers · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

J Mia Lahey-RudolphInstitute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.ORCID https://orcid.org/0000-0001-5279-7267
Robert SchönherrInstitute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.ORCID https://orcid.org/0000-0003-3850-4215
Miriam BarthelmessCenter for Free-Electron Laser Science (CFEL), Deutsches Elektronen Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg, Germany.
Pontus FischerCenter for Free-Electron Laser Science (CFEL), Deutsches Elektronen Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg, Germany.
Carolin SeuringCenter for Free-Electron Laser Science (CFEL), Deutsches Elektronen Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg, Germany.ORCID https://orcid.org/0000-0003-1000-0859
Armin WagnerDiamond Light Source, Diamond House DH2-52, Chilton, Didcot OX11 0DE, United Kingdom.ORCID https://orcid.org/0000-0001-8995-7324
Alke MeentsCenter for Free-Electron Laser Science (CFEL), Deutsches Elektronen Synchrotron (DESY), Notkestrasse 85, 22607 Hamburg, Germany.ORCID https://orcid.org/0000-0001-6078-4095
Lars RedeckeInstitute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
Universität Hamburg · DEDeutsches Elektronen-Synchrotron DESY · DEDiamond Light Source · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The crystallization of recombinant proteins in living cells is an exciting new approach in structural biology. Recent success has highlighted the need for fast and efficient diffraction data collection, optimally directly exposing intact crystal-containing cells to the X-ray beam, thus protecting the

Indexed as

fixed-target SFXin cellulo crystallographyintracellular protein crystalsRoadrunnerserial femtosecond crystallographysilicon chip

Identifiers

PMID34258014
PMCPMC8256716
OpenAlexW3174989006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.