Evidence map›Paper›PMID 34257893›Full record

ArticleChemical science2021

Thermodynamics of ion binding and occupancy in potassium channels.

Zhifeng Jing, Joshua A Rackers, Lawrence R Pratt, Chengwen Liu, Susan B Rempe, Pengyu Ren

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

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  7. Deciphering CaProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Effective polarization in potassium channel simulations: Ion conductance, occupancy, voltage response, and selectivity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  18. Development of AMOEBA Polarizable Force Field for Rare-Earth LaThe journal of physical chemistry. B · 2023
    Article
  19. AMOEBA Force Field Trajectories Improve Predictions of Accurate pThe journal of physical chemistry. B · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhifeng JingDepartment of Biomedical Engineering, The University of Texas at Austin Austin Texas 78712 USA pren@mail.utexas.edu.ORCID https://orcid.org/0000-0001-7013-036X
Joshua A RackersCenter for Integrated Nanotechnologies, Sandia National Laboratories Albuquerque New Mexico 87185 USA slrempe@sandia.gov.
Lawrence R PrattDepartment of Chemical and Biomolecular Engineering, Tulane University New Orleans Louisiana 70118 USA.
Chengwen LiuDepartment of Biomedical Engineering, The University of Texas at Austin Austin Texas 78712 USA pren@mail.utexas.edu.ORCID https://orcid.org/0000-0002-3930-7793
Susan B RempeCenter for Integrated Nanotechnologies, Sandia National Laboratories Albuquerque New Mexico 87185 USA slrempe@sandia.gov.
Pengyu RenDepartment of Biomedical Engineering, The University of Texas at Austin Austin Texas 78712 USA pren@mail.utexas.edu.
The University of Texas at Austin · USSandia National Laboratories · USTulane University · US

Funding

DEVELOPMENT OF A NEXT-GENERATION NUCLEIC ACID FORCE FIELDR01GM106137 · NIGMS · WASHINGTON UNIVERSITY · PI JAY PONDER, Pengyu Ren · 2013 to 2026
$3.5M
Specificity and Selectivity in Protein-Ion BindingR01GM114237 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI PONDER, JAY, REN, PENGYU · 2015 to 2023
$2.6M
NIGMS NIH HHS R01 GM106137NIGMS NIH HHS R01 GM114237
6 · The paper itself

Abstract

Potassium channels modulate various cellular functions through efficient and selective conduction of K

Identifiers

PMID34257893
PMCPMC8246295
OpenAlexW3166692788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.