Evidence map›Paper›PMID 34257877›Full record

ArticleChemical science2021

Carbene-catalyzed enantioselective annulation of dinucleophilic hydrazones and bromoenals for access to aryl-dihydropyridazinones and related drugs.

Bivas Mondal, Rakesh Maiti, Xing Yang, Jun Xu, Weiyi Tian, Jia-Lei Yan, Xiangyang Li, Yonggui Robin Chi

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 27 citations in OpenAlex.

  1. 4,5-Dihydro-2Molecules (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 4 countries.

Bivas MondalDivision of Chemistry & Mathematical Science, School of Physical & Mathematical Sciences, Nanyang Technological University Singapore 637371 Singapore robinchi@ntu.edu.sg.
Rakesh MaitiDivision of Chemistry & Mathematical Science, School of Physical & Mathematical Sciences, Nanyang Technological University Singapore 637371 Singapore robinchi@ntu.edu.sg.
Xing YangDivision of Chemistry & Mathematical Science, School of Physical & Mathematical Sciences, Nanyang Technological University Singapore 637371 Singapore robinchi@ntu.edu.sg.
Jun XuGuizhou University of Traditional Chinese Medicine Guiyang 550025 China tianweiyi@gzy.edu.cn.
Weiyi TianGuizhou University of Traditional Chinese Medicine Guiyang 550025 China tianweiyi@gzy.edu.cn.
Jia-Lei YanDivision of Chemistry & Mathematical Science, School of Physical & Mathematical Sciences, Nanyang Technological University Singapore 637371 Singapore robinchi@ntu.edu.sg.ORCID https://orcid.org/0000-0003-3804-9507
Xiangyang LiState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University Huaxi District Guiyang 550025 China xyli1@gzu.edu.cn.ORCID https://orcid.org/0000-0002-1502-1811
Yonggui Robin ChiState Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University Huaxi District Guiyang 550025 China xyli1@gzu.edu.cn.ORCID https://orcid.org/0000-0003-0573-257X
Nanyang Technological University · SGGuizhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

4,5-Dihydropyridazinones bearing an aryl substituent at the C6-position are important motifs in drug molecules. Herein, we developed an efficient protocol to access aryl-dihydropyridazinone molecules

Identifiers

PMID34257877
PMCPMC8246082
OpenAlexW3162329140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.