ArticleOxidative medicine and cellular longevity2021
New Markers of Platelet Activation and Reactivity and Oxidative Stress Parameters in Patients Undergoing Coronary Artery Bypass Grafting.
Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 19 citations in OpenAlex.
- Redox Imbalance and Coronary Complexity Linking Oxidative Stress Biomarkers to SYNTAX II Score in Acute Coronary Syndrome.Biomedicines · 2026Article
- Methodological and Pathophysiological Considerations in Obesity-Associated Thrombosis.International journal of molecular sciences · 2026Review
- Hematological parameters as predictors of complex angiographic coronary lesions in patients with acute myocardial infarction.PloS one · 2026Article
- Cardiovascular risk in patients with a relationship with oxidative stress and dyslipidemia.Journal of medical biochemistry · 2025Article
- EXPRESSION OF CONNEXIN-40 AND INTERLEUKIN 6 GENES IN PATIENTS WITH ATRIAL FIBRILLATION.Acta clinica Croatica · 2025Article
- The relationship between hematological parameters and coronary angiographic lesions.Frontiers in cardiovascular medicine · 2025Review
- Mean platelet volume might be an effective indicator of poor semen quality in varicocele patients.International urology and nephrology · 2024Article
- Cardiovascular Risk in Patients with Ankylosing Spondylitis.Journal of clinical medicine · 2024Article
- Designing an experimental method for assessing biocompatibility of circuit coatings using biomarkers for platelet activation during cardiopulmonary bypass.The journal of extra-corporeal technology · 2024Article
- The association between platelet-related parameters and nonalcoholic fatty liver disease in a metabolically healthy nonobese population.Scientific reports · 2024Article
- Neutrophil to albumin ratio: a biomarker in non-alcoholic fatty liver disease and with liver fibrosis.Frontiers in nutrition · 2024Article
- Effects of extracorporeal circulation with different time on platelet count after cardiac surgery: a retrospective study based on medical records.Scientific reports · 2023Article
- Comparative Study of Hematological Parameters and Biomarkers of Immunity and Inflammation in Patients with Psoriasis and Atopic Dermatitis.Medicina (Kaunas, Lithuania) · 2023Article
- Predictive Value of Red Blood Cell Distribution Width and Atrial Diameter in Paroxysmal Atrial Fibrillation: A Cross-Sectional Study.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
- Evaluation of Antioxidant Therapeutic Value of ACE Inhibitor as Adjunct Therapy on Type 2 Diabetes Mellitus Patients with Cardiovascular Disease.ACS pharmacology & translational science · 2022Article
- Association between inflammatory markers and non-alcoholic fatty liver disease in obese children.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveRecent studies have shown that the red cell distribution width- (RDW-) to-platelet (PLT) count ratio (i.e., RPR) and the mean platelet volume (MPV)/PLT ratio (i.e. MPR) are more sensitive markers of atherosclerosis-connected risk than RDW and PLT alone. The present study is aimed at investigating the oxidative stress status and these two new markers of platelet activation in two different heart surgery modalities: cardiopulmonary bypass (CPB) and off-pump coronary artery bypass (OPCAB). We also aimed to test the possible relationship between RPR and MPR, respectively, and the severity and complexity of atherosclerotic plaque, measured as Syntax Score.
resultsThe values of RPR and MPR were similar in CPB and OPCAB before surgery and started to rise in t2 (i.e., immediately after the intervention). This increase lasted to t5 (i.e., 48 hours after the intervention), when it became the highest. After that, both markers started to regress about the 96
conclusionWhen combined, MPV, RDW, and platelet count, such as MPR and RPR, could be good predictors of coronary artery disease status, regarding the aspect of joint inflammation, oxidative stress, and thrombosis.
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