Evidence map›Paper›PMID 34257807›Full record

ArticleOxidative medicine and cellular longevity2021

Physiological Dose of EGCG Attenuates the Health Defects of High Dose by Regulating MEMO-1 in

Yan Lu, Yi Wang, Li-Gui Xiong, Jian-An Huang, Zhong-Hua Liu, Yu-Shun Gong

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yan LuNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan 410128, China.ORCID https://orcid.org/0000-0002-4628-6556
Yi WangKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan 410128, China.
Li-Gui XiongNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan 410128, China.
Jian-An HuangKey Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, Hunan 410128, China.
Zhong-Hua LiuNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan 410128, China.ORCID https://orcid.org/0000-0003-0000-4565
Yu-Shun GongNational Research Center of Engineering and Technology for Utilization of Botanical Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, Hunan 410128, China.ORCID https://orcid.org/0000-0002-9534-5719
Hunan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EGCG, as a dietary-derived antioxidant, has been extensively studied for its beneficial health effects. Nevertheless, it induces the transient increase in ROS and leads to the hormetic extension of lifespan. How exactly biology-benefiting effects with the minimum severe adverse are realized remains unclear. Here, we showed that physiological dose of EGCG could help moderate remission in health side effects exposed to high doses, including shortened lifespan, reduced body size, decreased pharyngeal pumping rate, and dysfunctional body movement in

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCatechinIntracellular Signaling Peptides and ProteinsCaenorhabditis elegans ProteinsCatechinepigallocatechin gallateIntracellular Signaling Peptides and ProteinsMEMO1 protein, human

Identifiers

PMID34257807
PMCPMC8249131
OpenAlexW3176848538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.