Evidence map›Paper›PMID 34257806›Full record

ArticleOxidative medicine and cellular longevity2021

Schisandrol A Attenuates Myocardial Ischemia/Reperfusion-Induced Myocardial Apoptosis through Upregulation of 14-3-3

Shuaishuai Gong, Jincheng Liu, Shiyao Wan, Weiwei Yang, Yuanyuan Zhang, Boyang Yu, Fang Li, Junping Kou

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Phytochemical Analysis of the Extract from Berries ofInternational journal of molecular sciences · 2025
    Article
  5. Review
  6. Article
  7. A comprehensive review on Schisandrin and its pharmacological features.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. An analysis of the nutritional effects ofFrontiers in nutrition · 2023
    Review
  12. Article
  13. Investigating the Mechanism of Action ofDrug design, development and therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Shuaishuai Gong *Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-4563-0204
Jincheng Liu *Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0003-1991-4462
Shiyao WanJiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0003-3740-4415
Weiwei YangJiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-5317-1933
Yuanyuan ZhangJiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-3662-4398
Boyang YuJiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-1401-9250
Fang LiJiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0002-7617-6534
Junping KouJiangsu Key Laboratory of TCM Evaluation and Translational Research, Research Center for Traceability and Standardization of TCMs, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.ORCID https://orcid.org/0000-0001-8377-915X
China Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schisandrol A (SA), one of the most abundant bioactive lignans extracted from the

Indexed as

AnimalsApoptosisCyclooctanesLignansMaleMiceMyocardial Reperfusion InjuryMyocardiumTransfectionUp-RegulationCyclooctanesLignansschisandrol A

Identifiers

PMID34257806
PMCPMC8257380
OpenAlexW3175403158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.