A case of hepatic splenosis in the setting of iron overload; multimodal and literature review.

Lisa Richardson, Katie Gardner, Steven Eberhardt, William Thompson

Open access · goldAbstract readCase Reports

In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 86% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Hepatic Focal Lesion Suspicious for Hepatocellular Carcinoma in a Patient with a History of Post-Traumatic Splenectomy: The Challenge of Differential Diagnosis with Intrahepatic Splenosis-Literature Review and Case Report.Diagnostics (Basel, Switzerland) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lisa RichardsonDepartment of Radiology, UNM Hospital, 2211 Lomas Blvd NE, Albuquerque, NM, USA.

Katie GardnerDepartment of Radiology, UNM Hospital, 2211 Lomas Blvd NE, Albuquerque, NM, USA.

Steven EberhardtDepartment of Radiology, UNM Hospital, 2211 Lomas Blvd NE, Albuquerque, NM, USA.

William ThompsonDepartment of Radiology, UNM Hospital, 2211 Lomas Blvd NE, Albuquerque, NM, USA.

University of New Mexico Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic splenosis, a rare entity, is the ectopic implantation of splenic tissue into the hepatic parenchyma, most often incidentally seen in patients with a history of splenic trauma and splenectomy. We present a unique case of hepatic splenosis in a patient with hemosiderosis and splenectomy following the incidental finding of hepatic masses on pretransplant imaging. Final diagnosis was made based on cross-sectional imaging characteristics matching that of the left upper quadrant splenules alone. We discuss common characteristics of hepatic splenosis on multiple modalities, the effect of iron deposition on the imaging characteristics of hepatic and splenic tissue and how that impacts the differential and diagnosis. This case highlights the unique imaging characteristics hepatic splenosis can have particularly in the setting of hemosiderosis. Hepatic splenosis imaging diagnosis has a significant advantage over tissue diagnosis in terms of decreased risk, time and cost.

Indexed as

CT, Computed TomographyESRD, End Stage Renal DiseaseHemosiderosisHepatic massesHepatic splenosisHS, Hepatic SplenosisIron depositionIron overloadMRI, Magnetic Resonance ImagingSiderosisSplenectomySplenosisTc-99m-DRBC, Tc-99m labelled heat-denatured red blood cellsUS, Ultrasound

Identifiers

PMID34257788

DOI10.1016/j.radcr.2021.05.037

PMCPMC8259227

OpenAlexW3181007051

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.