Evidence map›Paper›PMID 34257785›Full record

ArticleRadiology case reports2021

Transient regional osteoporosis of the hip with extensive bone marrow edema (BME): Dramatic improvement after three months of Alendronate therapy.

Yasser Emad, Yasser Ragab, Mariam Ahmed Saad, Johannes J Rasker

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Yasser EmadRheumatology Department, Faculty of Medicine, Cairo University, Kasr Alainy St, 11562 Cairo, Egypt.
Yasser RagabRadiology Department , Dr. Erfan and Bagedo General Hospital , King Fahad St. (Al Sitteen), 21452, Jeddah, Saudi Arabia.
Mariam Ahmed SaadMedical Oncology Department, National Cancer Institute, Cairo, Egypt.
Johannes J RaskerFaculty of Behavioral, Management and Social Sciences, Department Psychology, Health and Technology, University of Twente, Drienerlolaan 5, 7522NB Enschede, the Netherlands.
Cairo University · EGChildren Cancer Hospital · EGUniversity of Twente · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transient osteoporosis of the hip, also termed transient bone marrow edema, is a painful condition often occurring after trivial trauma. It can be diagnosed with MRI in patients whose radiographs are negative or inconclusive. In this case report we describe a 39-year-old female patient with this rare entity, who was successfully treated with oral Alendronate, active vitamin D and calcium supplementation combined with avoiding of weight bearing on the affected hip. She improved clinically within three months and on contrast enhanced MRI studies, as performed before and after treatment, complete regression of bone marrow edema was shown already after three months of treatment. The literature was reviewed regarding the pathophysiology of transient osteoporosis of the hip and the beneficial effects of Alendronate in this domain. The report is important because it will increase the awareness among clinicians and radiologists about this entity, as in neglected cases transient regional osteoporosis of the hip may progress to avascular necrosis with complete loss of hip function.

Indexed as

AlendronateAVN, avascular necrosisBME, Bone marrow edemaBMES, Bone marrow edema syndromesFAI, femoro-acetabular impingementMRI, magnetic resonance imagingRMO, regional migratory osteoporosisRSD, reflex sympathetic dystrophySTIR, short tau inversion recoveryTBME, transient Bone marrow edemaTOH, transient osteoporosis of the hipTransient bone marrow edema syndromeTransient regional osteoporosis of the hip

Identifiers

PMID34257785
PMCPMC8259220
OpenAlexW3180471016

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.