Evidence map›Paper›PMID 34257784›Full record

ArticleRadiology case reports2021

A patient with multiple brown tumors due to secondary hyperparathyroidism: A case report.

Laura Messina, A Garipoli, F M Giordano, U Ferrari, R Grippo, M Sarli, B Beomonte Zobel

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Massive brown tumors of the jaw: A case report.SAGE open medical case reports · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Laura MessinaDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
A GaripoliDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
F M GiordanoDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
U FerrariDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
R GrippoDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
M SarliDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
B Beomonte ZobelDepartment of Radiology, University of Rome "Campus Bio-medico", Via Alvaro del Portillo, 21- 00128 Rome, Italy.
Università Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brown tumor is an uncommon non-neoplastic radiolucent bone lesion due to a rapid bone loss replaced by haemorrhage and reparative granulation tissue. It is a manifestation of hyperparathyroidism related to the high level of parathyroid hormone and represents a problem linked to the adherence to therapy. We present a case of a 44 years-old Caucasian female with hemodialysis-dependent chronic kidney disease in poor sanitary condition with CT evidence of innumerable and widespread bone tumors. At first, we considered these bone lesions strongly suspicious for metastasis, so we recommended an oncological consultation and laboratory studies, that showed a secondary hyperparathyroidism with elevated serum parathormone level of 923 pg/mL (normal range: 10-70 pg/mL). According to our experience, in case of radiological evidence of multiple bone lesions, a correct medical history is mandatory. When the patient has a history of chronic kidney disease and dialysis and high blood levels of parathyroid hormone are present, secondary hyperparathyroidism should always be considered in the differential diagnosis.

Indexed as

bone lesionsbrown tumorsCT scanHyperparathyroidism

Identifiers

PMID34257784
PMCPMC8260758
OpenAlexW3178402366

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.