Evidence map›Paper›PMID 34257748›Full record

ArticleDisease markers2021

TNF-

Adrian Groh, Kirsten Jahn, Marc Walter, Johannes Heck, Ralf Lichtinghagen, Eva Janke, Martin Lennart Schulze Westhoff, Maximillian Deest, Helge Frieling, Stefan Bleich and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Adrian GrohDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-4407-3557
Kirsten JahnDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-2760-1602
Marc WalterDepartment of Psychiatry (UPK), University of Basel, Basel, Switzerland.ORCID 0000-0002-2238-2017
Johannes HeckInstitute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-5382-3014
Ralf LichtinghagenInstitute of Clinical Chemistry, Hannover Medical School, Hannover, Hannover, Germany.ORCID 0000-0003-4659-9453
Eva JankeDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-5671-1990
Martin Lennart Schulze WesthoffDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0003-3262-8137
Maximillian DeestDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-8759-8660
Helge FrielingDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0001-5146-9720
Stefan BleichDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0001-5004-3824
Kai G KahlDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-8530-0605
Annemarie HeberleinDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany.ORCID 0000-0003-2505-0576
Medizinische Hochschule Hannover · DEUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The model of neuroinflammation has been proposed as a possible explanation of depression. Investigations of serum levels of tumor necrosis factor- Methods: We compared the serum levels of TNF- Results: We observed a statistically significant increase of TNF- Conclusion: As TNF-

Indexed as

AdultBiomarkersCohort StudiesDepressionFemaleHumansMaleMiddle AgedNeuroinflammatory DiseasesPsychiatric Status Rating ScalesPsychotherapyTreatment OutcomeTumor Necrosis Factor-alphaBiomarkersTumor Necrosis Factor-alpha

Identifiers

PMID34257748
PMCPMC8249748
OpenAlexW3138774164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.