Evidence map›Paper›PMID 34257739›Full record

ArticleBehavioural neurology2021

Association between Genetic Variants in

Fang Fang, Minxia Ge, Jun Liu, Zengyu Zhang, Hong Yu, Shuilong Zhu, Liwei Xu, Lina Shao

Open access · goldAbstract read
In one paragraph

Article in Behavioural neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Fang FangDepartment of Clinical Laboratory, The Third People's Hospital of Xiaoshan District, Hangzhou, China.
Minxia GeDepartment of Clinical Laboratory, The Third People's Hospital of Xiaoshan District, Hangzhou, China.
Jun LiuCentral Laboratory, Department of Clinical Laboratory, Zhejiang Xiaoshan Hospital, Hangzhou, China.ORCID https://orcid.org/0000-0003-4132-4450
Zengyu ZhangDepartment of Pediatrics, Xiaoshan First Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Hong YuDepartment of Clinical Psychology, Xiaoshan First Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Shuilong ZhuDepartment of Clinical Laboratory, The Third People's Hospital of Xiaoshan District, Hangzhou, China.
Liwei XuDepartment of Clinical Laboratory, The Third People's Hospital of Xiaoshan District, Hangzhou, China.
Lina ShaoDepartment of Clinical Laboratory, The Third People's Hospital of Xiaoshan District, Hangzhou, China.
The First People's Hospital of Xiaoshan District, Hangzhou · CNAffiliated Hospital of Hangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGenetic factors play an important role in the development of autism spectrum disorder (ASD). This case-control study was to determine the association between childhood ASD and single nucleotide polymorphisms (SNPs) rs3746599 in the

methodsGenotypes of SNPs were examined in DNA extracted from blood cells from 201 children with ASD and 200 healthy controls. The Children Autism Rating Scale (CARS) was applied to evaluate the severity of the disease and language impairment. The relationship between SNPs and the risk of ASD or the severity of the disease was determined by logistic regression and one-way ANOVA.

resultsThe genotype G/G of rs3746599 in the

conclusionsOur findings suggest that both rs3746599 in the

Indexed as

Autism Spectrum DisorderAutistic DisorderDual-Specificity PhosphatasesMembrane ProteinsNerve Tissue ProteinsCase-Control StudiesChildGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideCNTNAP2 protein, humanDual-Specificity PhosphatasesDUSP15 protein, humanMembrane ProteinsNerve Tissue Proteins

Identifiers

PMID34257739
PMCPMC8261179
OpenAlexW3173576740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.