Evidence map›Paper›PMID 34257646›Full record

ArticleAdvances in urology2021

Penile Hemodynamic Response to Phosphodiesterase Type V Inhibitors after Cavernosal Sparing Inflatable Penile Prosthesis Implantation: A Prospective Randomized Open-Blinded End-Point (PROBE) Study.

Adham Zaazaa, Michaela Bayerle-Eder, Ramzy Elnabarawy, Mahmoud Elbitar, Taymour Mostafa

Registry-linked trialAbstract read
In one paragraph

Article in Advances in urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05531877 (Penile Implant Intraoperative Measurements Planning Chart), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05531877 naunknown statusnot on this map

Penile Implant Intraoperative Measurements Planning Chart

TypeinterventionalSponsorCairo UniversityRan2020 to 2022Enrolled200ConditionsErectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction With Diabetes Mellitus, Erectile Dysfunction Due to Arterial DiseaseArmsPenile Prosthesis Implantation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adham ZaazaaDepartment of Andrology, Sexology & STIs, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.ORCID https://orcid.org/0000-0002-4999-5390
Michaela Bayerle-EderDepartment of Endocrinology & Metabolism, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.
Ramzy ElnabarawyDepartment of Andrology, Sexology & STIs, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.ORCID https://orcid.org/0000-0003-2114-3986
Mahmoud ElbitarDepartment of Andrology, Sexology & STIs, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.
Taymour MostafaDepartment of Andrology, Sexology & STIs, Faculty of Medicine, Cairo University, Cairo 11562, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Forceful corporal dilatation amidst penile prosthesis implantation may injure cavernosal arteries compromising penile vasculature. In this study, we aimed to compare the conventional and cavernosal sparing techniques regarding cavernosal artery preservation. Overall, 33 patients underwent inflatable penile prosthesis implantation with Coloplast Titan Touch® three-piece inflatable penile implants. 16 patients had conventional implantations with serial vigorous dilatations, while 17 patients were implanted with the cavernosal sparing technique, consisting of a single minimal corporal dilatation after an intraoperative intracavernosal injection (ICI) of Alprostadil. Postoperatively, a penile duplex Doppler ultrasound study was performed. Whenever a cavernosal artery was spared and thus successfully probed, its hemodynamics were studied before and after an oral administration of a phosphodiesterase type 5 inhibitor (PDE5i). A cavernosal artery was successfully probed in 16/17 (94%) of patients in the cavernosal sparing group compared to 5/16 (31%) of patients in the conventional group with a significant statistical difference (

Identifiers

PMID34257646
PMCPMC8257370

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.