Evidence map›Paper›PMID 34257639›Full record

ArticleNeural plasticity2021

The Anticonvulsant Effect of Hydroethanolic Leaf Extract of

Ernest Obese, Robert Peter Biney, Isaac Tabiri Henneh, Emmanuel Awintiig Adakudugu, Daniel Anokwah, Lovia Serwaa Agyemang, Eric Woode, Elvis Ofori Ameyaw

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Unveiling the therapeutic potential of Calotropis procera: from traditional applications to phytochemistry, pharmacology, and safety.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ernest ObeseSchool of Pharmacy and Pharmaceutical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0001-6903-7774
Robert Peter BineySchool of Pharmacy and Pharmaceutical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-7566-5387
Isaac Tabiri HennehSchool of Pharmacy and Pharmaceutical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-6830-0283
Emmanuel Awintiig AdakuduguSchool of Pharmacy and Pharmaceutical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-6254-6397
Daniel AnokwahSchool of Pharmacy and Pharmaceutical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0001-7086-9332
Lovia Serwaa AgyemangDepartment of Biomedical Sciences, School of Allied Health Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0003-2204-8059
Eric WoodeDepartment of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, University of Allied Health Sciences, Ho, Ghana.ORCID 0000-0002-2182-5736
Elvis Ofori AmeyawSchool of Pharmacy and Pharmaceutical Sciences, College of Health and Allied Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID 0000-0002-8317-9602
University of Cape Coast · GHUniversity of Health and Allied Sciences · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A number of currently used drugs have been obtained from medicinal plants which are a major source of drugs. These drugs are either used in their pure form or modified to a semisynthetic drug. Drug discovery through natural product research has been fruitful over the years. Traditionally,

Indexed as

AnimalsAnticonvulsantsCalotropisChromatography, High Pressure LiquidConvulsantsDiazepamDrug Evaluation, PreclinicalEthanolFemaleFlumazenilIsoniazidMaleMiceMice, Inbred ICRPhytotherapyPicrotoxinAnticonvulsantsConvulsantsDiazepamEthanolFlumazenilIsoniazidPicrotoxinPilocarpinePlant ExtractsReceptors, GABA-ASolventsStrychnineWater

Identifiers

PMID34257639
PMCPMC8257368
OpenAlexW3176616811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.