Evidence map›Paper›PMID 34257632›Full record

ArticleBioinorganic chemistry and applications2021

S100A8/A9 Molecular Complexes Promote Cancer Migration and Invasion via the p38 MAPK Pathway in Nasopharyngeal Carcinoma.

Ning Xu, Bei-Bei Zhang, Xia-Ning Huang, Xiang Yi, Xue-Min Yan, Yan Cai, Qin He, Zi-Jian Han, Yuan-Jiao Huang, Wei Liu and 1 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Bioinorganic chemistry and applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

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  10. Osimertinib Improves Overall Survival in Patients with Leptomeningeal Metastases Associated withEvidence-based complementary and alternative medicine : eCAM · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ning XuThe Fifth Affiliated Hospital of Guangxi Medical University, Nanning, China.
Bei-Bei ZhangInstitute of Biomedical Research, Yunnan University, Kunming, China.
Xia-Ning HuangWuming Hospital of Guangxi Mediacal University, Nanning, China.
Xiang YiDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xue-Min YanGraduate School of Guangxi Medical University, Nanning, China.
Yan CaiGraduate School of Guangxi Medical University, Nanning, China.
Qin HeGraduate School of Guangxi Medical University, Nanning, China.
Zi-Jian HanGraduate School of Guangxi Medical University, Nanning, China.ORCID https://orcid.org/0000-0002-8829-8766
Yuan-Jiao HuangLife Science Institute, Guangxi Medical University, Nanning, China.ORCID https://orcid.org/0000-0002-1867-3751
Wei LiuPharmaceutical College, Guangxi Medical University, Nanning, China.ORCID https://orcid.org/0000-0002-3632-2672
Ai-Jun JiaoPharmaceutical College, Guangxi Medical University, Nanning, China.ORCID https://orcid.org/0000-0002-0024-5476
Guangxi Medical University · CNYunnan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasopharyngeal carcinoma (NPC) is one type of malignancy associated with migration and invasion through a currently unclear mechanism. We previously discovered S100A8/A9 levels were roughly elevated in the plasma of NPC patients as the promising biomarkers. However, their expressions and underlying functions in NPC tissues are still unknown. In the present study, we analyzed 49 NPC tissues and 20 chronic pharyngitis (CP) tissues. Immunohistochemical staining was performed in different tissues and analyzed by the Mann-Whitney

Identifiers

PMID34257632
PMCPMC8245251
OpenAlexW3173526158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.