Evidence map›Paper›PMID 34257620›Full record

ArticlePathology oncology research : POR2021

The Impact of IDH1 Mutation and MGMT Promoter Methylation on Recurrence-Free Interval in Glioblastoma Patients Treated With Radiotherapy and Chemotherapeutic Agents.

Maher Kurdi, Nadeem Shafique Butt, Saleh Baeesa, Badrah Alghamdi, Yazid Maghrabi, Anas Bardeesi, Rothaina Saeedi, Taghreed Al-Sinani, Najla Alghanmi, Mohammed O Bari and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Correlations ofMolecular and clinical oncology · 2025
    Article
  3. Genetic and epigenetic landscape of OExploration of targeted anti-tumor therapy · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Maher KurdiDepartment of Pathology, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
Nadeem Shafique ButtDepartment of Family and Community Medicine, Faculty of Medicine in Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia.
Saleh BaeesaDivision of Neurosurgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Badrah AlghamdiDepartment of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Yazid MaghrabiDepartment of Neuroscience, King Faisal Specialist Hospital, Jeddah, Saudi Arabia.
Anas BardeesiDepartment of Neuroscience, King Faisal Specialist Hospital, Jeddah, Saudi Arabia.
Rothaina SaeediDivision of Neurosurgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Taghreed Al-SinaniDepartment of Surgery,Division of Neurosurgery, King Fahad General Hospital, Jeddah, Saudi Arabia.
Najla AlghanmiDepartment of Pathology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Mohammed O BariDepartment of Pathology, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Alaa SamkariDepartment of Pathology and Laboratory Medicine, King Saud Bin Abdulaziz University for Health Science, Jeddah, Saudi Arabia.
Ahmed I LarySection of Neurosurgery, Department of Surgery, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
King Abdulaziz University · SAKing Abdulaziz Hospital · SAKing Abdulaziz Medical City · SAKing Fahad Hospital Jeddah · SAKing Faisal Specialist Hospital & Research Centre · SAKing Saud bin Abdulaziz University for Health Sciences · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to investigate the relationship between isocitrate dehydrogenase-1 (

Indexed as

DNA MethylationBiomarkers, TumorBrain NeoplasmsChemoradiotherapyDNA Modification MethylasesDNA Repair EnzymesFemaleFollow-Up StudiesGene Expression Regulation, NeoplasticGlioblastomaHumansIsocitrate DehydrogenaseMaleMiddle AgedNeoplasm Recurrence, LocalPrognosisBiomarkers, TumorDNA Modification MethylasesDNA Repair EnzymesIDH1 protein, humanIsocitrate DehydrogenaseMGMT protein, humanTumor Suppressor ProteinschemotherapyglioblastomaIDH1 mutationMGMT promoter methylationradiotherapy

Identifiers

PMID34257620
PMCPMC8262235
OpenAlexW3158307175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.