Evidence map›Paper›PMID 34257602›Full record

ArticlePathology oncology research : POR2021

HDAC Inhibition Induces Cell Cycle Arrest and Mesenchymal-Epithelial Transition in a Novel Pleural-Effusion Derived Uterine Carcinosarcoma Cell Line.

Paul Stockhammer, Özlem Okumus, Luca Hegedus, Dominika Rittler, Till Ploenes, Thomas Herold, Stavros Kalbourtzis, Agnes Bankfalvi, Antje Sucker, Rainer Kimmig and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Uterine carcinosarcoma: Unraveling the role of epithelial-to-mesenchymal transition in progression and therapeutic potential.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Paul StockhammerDepartment of Thoracic Surgery, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Özlem OkumusDepartment of Thoracic Surgery, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Luca HegedusDepartment of Thoracic Surgery, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Dominika Rittler2nd Institute of Pathology, Semmelweis University, Budapest, Hungary.
Till PloenesDepartment of Thoracic Surgery, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Thomas HeroldInstitute of Pathology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Stavros KalbourtzisInstitute of Pathology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Agnes BankfalviInstitute of Pathology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Antje SuckerDepartment of Dermatology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Rainer KimmigDepartment of Gynecology and Obstetrics, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Clemens AignerDepartment of Thoracic Surgery, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Balazs HegedusDepartment of Thoracic Surgery, Ruhrlandklinik, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
University of Duisburg-Essen · DEMedical University of Vienna · ATSemmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell Cycle CheckpointsEpithelial-Mesenchymal TransitionAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorCarcinosarcomaCisplatinFemaleGene Expression Regulation, NeoplasticHistone DeacetylasesHumansMiddle AgedMutationPaclitaxelPhthalazinesPiperazinesPleural Effusion, MalignantBiomarkers, TumorCisplatinHistone DeacetylasesLY-2157299olaparibPaclitaxelPhthalazinesPiperazinesPyrazolesQuinolinesVorinostatARID1Aepithelial-mesenchymal transitionHDAC inhibitionmesenchymal-epithelial transitiontargeted therapyuterine carcinosarcoma

Identifiers

PMID34257602
PMCPMC8262245
OpenAlexW3146545499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.