Evidence map›Paper›PMID 34257594›Full record

ArticlePathology oncology research : POR2021

Hyperoside Protects HK-2 Cells Against High Glucose-Induced Apoptosis and Inflammation

Jingbo Zhou, Shu Zhang, Xinyi Sun, Yan Lou, Jiangyi Yu

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Hyperoside AlleviatesPolish journal of microbiology · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jingbo ZhouDepartment of Endocrinology, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, China.
Shu ZhangDepartment of Endocrinology, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, China.
Xinyi SunDepartment of Endocrinology, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, China.
Yan LouDepartment of Endocrinology, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, China.
Jiangyi YuDepartment of Endocrinology, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing, China.
Nanjing University of Chinese Medicine · CNJiangsu Provincial Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperoside, a flavonol glycoside, is derived from plants of the genera

Indexed as

ApoptosisAdaptor Proteins, Signal TransducingCarcinoma, Renal CellCell ProliferationGene Expression RegulationGlucoseHumansInflammationKidney NeoplasmsKidney Tubules, ProximalMicroRNAsNuclear ProteinsProtective AgentsQuercetinSweetening AgentsTumor Cells, CulturedAdaptor Proteins, Signal TransducingDCAF6 protein, humanGlucosehyperosideMicroRNAsMIRN499 microRNA, humanNuclear ProteinsProtective AgentsQuercetinSweetening AgentsapoptosisHK-2 cellshyperosideinflammationmolecular biology

Identifiers

PMID34257594
PMCPMC8262192
OpenAlexW3156528448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.