Evidence map›Paper›PMID 34257546›Full record

ArticlePathology oncology research : POR2021

Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous

Lydia Meder, Alexandra Florin, Luka Ozretić, Marieke Nill, Mirjam Koker, Sonja Meemboor, Freddy Radtke, Linda Diehl, Roland T Ullrich, Margarete Odenthal and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Lydia MederDepartment I of Internal Medicine, University Hospital Cologne, Cologne, Germany.
Alexandra FlorinInstitute for Pathology, University Hospital Cologne, Cologne, Germany.
Luka OzretićDepartment of Cellular Pathology, Royal Free Hospital, London, United Kingdom.
Marieke NillDepartment I of Internal Medicine, University Hospital Cologne, Cologne, Germany.
Mirjam KokerDepartment I of Internal Medicine, University Hospital Cologne, Cologne, Germany.
Sonja MeemboorInstitute for Pathology, University Hospital Cologne, Cologne, Germany.
Freddy RadtkeÉcole Polytechnique Fédérale de Lausanne, Swiss Institute for Experimental Cancer Research Lausanne, Switzerland.
Linda DiehlInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Roland T UllrichDepartment I of Internal Medicine, University Hospital Cologne, Cologne, Germany.
Margarete OdenthalCenter for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Reinhard BüttnerCenter for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
Lukas C HeukampInstitute for Hematopathology Hamburg, Hamburg, Germany.
University Hospital Cologne · DEUniversity of Cologne · DEÉcole Polytechnique Fédérale de Lausanne · CHInstitut für Hämatopathologie Hamburg · DEThe Royal Free Hospital · GBUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalMutationAcyltransferasesAdenocarcinoma of LungAnimalsApoptosisBiomarkers, TumorBronchiCarcinogenesisCarcinoma, Squamous CellCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansLung NeoplasmsMaleAcyltransferasesBiomarkers, TumorKRAS protein, humanProto-Oncogene Proteins p21(ras)Receptor, Notch1tafazzin protein, mouseKRASlung cancermouse modelNOTCH1TAZ

Identifiers

PMID34257546
PMCPMC8262161
OpenAlexW3152841074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.