Evidence map›Paper›PMID 34257530›Full record

ArticlePathology oncology research : POR2021

Overexpression of PELP1 in Lung Adenocarcinoma Promoted E

Dongmei Zhang, Jiali Dai, Yu Pan, Xiuli Wang, Juanjuan Qiao, Hironobu Sasano, Baoshan Zhao, Keely M McNamara, Xue Guan, Lili Liu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Pathology oncology research : POR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. PELP1 expression is associated with disease progression in inflammation-driven oral cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Dongmei ZhangDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Jiali DaiDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Yu PanDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Xiuli WangDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Juanjuan QiaoDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Hironobu SasanoDepartment of Pathology, Tohoku University School of Medicine, Sendai, Japan.
Baoshan ZhaoDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Keely M McNamaraDepartment of Pathology, Tohoku University School of Medicine, Sendai, Japan.
Xue GuanDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Lili LiuDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Yanzhi ZhangDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Monica S M ChanDepartment of Pathology, Tohoku University School of Medicine, Sendai, Japan.
Shuwen CaoDepartment of Pathology, Daqing Oilfield General Hospital, Daqing, China.
Ming LiuDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Sihang SongDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Lin WangDepartment of Pathology, Harbin Medical University-Daqing, Daqing, China.
Daqing City People's Hospital · CNHarbin Medical University · CNTohoku University · JPDaqing Oilfield General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression of Proline-, glutamic acid-, and leucine-rich protein 1 (PELP1) has been reported to be dysregulated in non-small cell lung carcinoma, especially in lung adenocarcinoma (LUAD). Therefore, we aimed to investigate the functional and prognostic roles of PELP1 in LUAD in this study. We first immunolocalized PELP1 in 76 cases of LUAD and 17 non-pathological or tumorous lung (NTL) tissue specimens and correlated the findings with the clinicopathological parameters of the patients. We then performed

Indexed as

Adenocarcinoma of LungCell Line, TumorCell MovementCell ProliferationCo-Repressor ProteinsEstradiolEstrogen Receptor alphaEstrogen Receptor betaFemaleHumansLung NeoplasmsLymphatic MetastasisMaleMiddle AgedPrognosisSurvival RateCo-Repressor ProteinsEstradiolEstrogen Receptor alphaEstrogen Receptor betaPELP1 protein, humanTranscription Factorsestrogenglutamic acid-leucine-rich protein 1lung adenocarcinomaproline-tumor progression

Identifiers

PMID34257530
PMCPMC8262236
OpenAlexW3151563324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.