Evidence map›Paper›PMID 34257397›Full record

ArticleScientific reports2021

Risk factors for urosepsis in chronic kidney disease patients with urinary tract infections.

Zorica Dimitrijevic, Goran Paunovic, Danijela Tasic, Branka Mitic, Dragoslav Basic

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05674942 (Urinary Tract Infection in Patients With Chronic Kidney Disease), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05674942 completednot on this mapstarted 2023, after this paper: background citation

Urinary Tract Infection in Patients With Chronic Kidney Disease: A Retrospective Observational Study at Outpatient Nephrology Clinics

TypeobservationalSponsorAlexandria UniversityRan2023 to 2024Enrolled250ConditionsUrinary Tract Infections, Chronic Kidney DiseasesArmsPatients with urinary tract infection and chronic kidney disease
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
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  13. Article
  14. Mouse Models of Sepsis.Current protocols · 2024
    Article
  15. Article
  16. Article
  17. Development of a High-Throughput Urosepsis Mouse Model.Pathogens (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zorica DimitrijevicFaculty of Medicine, University of Nis, Bulevar Dr. Z. Djindjica 81, 18000, Niš, Serbia. zorica_mdimitrijevic@yahoo.com.ORCID 0000-0002-4944-1822
Goran PaunovicClinic for Nephrology, Clinical Center Nis, Bulevar Dr. Z. Djindjica 48, 18000, Niš, Serbia.
Danijela TasicClinic for Nephrology, Clinical Center Nis, Bulevar Dr. Z. Djindjica 48, 18000, Niš, Serbia.
Branka MiticFaculty of Medicine, University of Nis, Bulevar Dr. Z. Djindjica 81, 18000, Niš, Serbia.
Dragoslav BasicFaculty of Medicine, University of Nis, Bulevar Dr. Z. Djindjica 81, 18000, Niš, Serbia.
University of Nis · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occurrence of urosepsis is not uncommon following urinary tract infections (UTI). However, there is a lack of evidence explaining the risk factors predisposing to urosepsis in patients with chronic kidney disease (CKD). This retrospective study was undertaken to evaluate the incidence and possible risk factors for urosepsis among patients hospitalized with UTI in a cohort of CKD patients. Patients were divided into the urosepsis group and the non-urosepsis group. Of 489 hospitalized patients with UTI, 70 (14.3%) acquired urosepsis. Stepwise multivariate logistic regression demonstrated that diabetes, urinary catheter and length of hospital stay (p < 0.001 for all) were significant independent predictive risk factors for urosepsis in CKD patients with UTI in addition to age, glomerular filtration rate, hydronephrosis, acute kidney injury and E. coli infection (p < 0.05 for all). Finally, Klebsiella spp. cases were associated with significantly higher odds for urosepsis than E. coli cases (OR: 3.5, 95% CI: 2.86-7.23, p < 0.001 vs. OR: 1.38, 95% CI: 1.19-3.69, p = 0.038). Diabetes, presence of an indwelling urinary catheter, length of hospitalization, and infection with Klebsiella spp were independent risk factors for urosepsis in CKD patients with UTI.

Indexed as

Renal Insufficiency, ChronicSepsisUrinary Tract InfectionsAdultAgedEscherichia coli InfectionsFemaleGlomerular Filtration RateHumansIncidenceLength of StayMaleMiddle AgedRetrospective StudiesRisk Factors

Identifiers

PMID34257397
PMCPMC8277778
OpenAlexW3180193901

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.