Evidence map›Paper›PMID 34257396›Full record

ArticleScientific reports2021

Associations between lifetime classic psychedelic use and cardiometabolic diseases.

Otto Simonsson, Walter Osika, Robin Carhart-Harris, Peter S Hendricks

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Psilocybin: From Psychiatric Pariah to Perceived Panacea.The American journal of psychiatry · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Psychedelics and workplace harm.Frontiers in psychiatry · 2023
    Article
  17. Association between Lifetime Classic Psychedelic Use and Sick Leave in a Population-Based Sample.International journal of environmental research and public health · 2022
    Article
  18. Psychedelics in the treatment of unipolar and bipolar depression.International journal of bipolar disorders · 2022
    Review
  19. Article
  20. Classic psychedelics, health behavior, and physical health.Therapeutic advances in psychopharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Otto SimonssonDepartment of Sociology, University of Oxford, Oxford, UK. otto.simonsson@trinity.ox.ac.uk.ORCID 0000-0003-4197-7566
Walter OsikaDepartment of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institute, Solna, Sweden.
Robin Carhart-HarrisCentre for Psychedelic Research, Imperial College London, London, UK.
Peter S HendricksDepartment of Health Behavior, University of Alabama at Birmingham, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the current study was to investigate the associations between lifetime classic psychedelic use and cardiometabolic diseases. Using data from the National Survey on Drug Use and Health (2005-2014), the present study examined the associations between lifetime classic psychedelic use and two types of cardiometabolic disease: heart disease and diabetes. Respondents who reported having tried a classic psychedelic at least once in their lifetime had lower odds of heart disease in the past year (adjusted odds ratio (aOR) = 0.77 (0.65-0.92), p = .006) and lower odds of diabetes in the past year (adjusted odds ratio (aOR) = 0.88 (0.78-0.99), p = .036). Classic psychedelic use might be beneficial for cardiometabolic health, but more research is needed to investigate potential causal pathways of classic psychedelics on cardiometabolic diseases.

Indexed as

HallucinogensAdolescentAdultCardiovascular DiseasesDiabetes MellitusFemaleHeart DiseasesHumansMaleMiddle AgedOdds RatioYoung AdultHallucinogens

Identifiers

PMID34257396
PMCPMC8277805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.