Evidence map›Paper›PMID 34257322›Full record

ArticleScientific reports2021

Atypical periprosthetic femoral fractures after arthroplasty for fracture are at high risk of complications.

Tomonori Baba, Masataka Uchino, Hironori Ochi, Takuya Ikuta, Yoshitomo Saita, Hiroshi Hagino, Hiroaki Nonomiya, Seiya Jingushi, Takayuki Nakajima, Yasuhisa Ueda and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Influence of bone quality on femoral stress distribution after cemented stem insertion: an experimental thermoelastic stress analysis.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2026
    Article
  2. Article
  3. Article
  4. The definition of atypical femoral fractures should include periprosthetic femoral fractures (PAFFs).Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Tomonori BabaDepartment of Orthopaedic Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan. tobaba@juntendo.ac.jp.ORCID 0000-0002-9473-6224
Masataka UchinoDepartment of Orthopaedic Surgery, Hakujikai Memorial Hospital, Tokyo, Japan.
Hironori OchiDepartment of Orthopaedic Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Takuya IkutaKumamoto Orthopedic Hospital, Kumamoto, Japan.
Yoshitomo SaitaDepartment of Orthopaedic Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Hiroshi HaginoSchool of Health Science, Tottori University, Tottori, Japan.
Hiroaki NonomiyaDepartment of Orthopaedic Surgery, Shizuoka Red Cross Hospital, Shizuoka, Japan.
Seiya JingushiDepartment of Orthopaedic Surgery, Kyushu Rosai Hospital, Kitakyushu, Japan.
Takayuki NakajimaDepartment of Orthopaedic Surgery, Eastern Chiba Medical Center, Chiba, Japan.
Yasuhisa UedaDivision of Orthopaedic Trauma, Sapporo Tokushukai Hospital, Sapporo, Japan.
Kaneko KazuoDepartment of Orthopaedic Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.
Juntendo University · JPKumamoto Orthopedic Surgery Hospital · JPKyushu Rosai Hospital · JPSapporo Higashi Tokushukai Hospital · JPShizuoka Red Cross Hospital · JPTeikyo University Chiba Medical Center · JPTottori University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is difficult to investigate clinical features in a single-center study because atypical periprosthetic femoral fracture (APFF) is rare. This study aims to perform a nationwide survey of APFF to investigate the characteristics of this fracture and compare the clinical outcome with that of typical periprosthetic femoral fracture (typical PFF). A nationwide survey was performed asking for cooperation from 183 councilors of the Japanese Society for Fracture Repair. The subjects were patients with APFF injured between 2008 and 2017. The control group was comprised of patients with typical PFF of our facility injured in the same period. A total of 43 patients met the APFF definition. The control group was comprised of 75 patients with typical PFF. The rate of bisphosphonate use was significantly higher in the APFFs group than in the typical PFF group (62.8% and 32%, p < 0.02). The rate of cemented stem was significantly higher in the APFFs group than in the typical PFF group (30.2% and 6.7%, p < 0.001). In the patients with arthroplasty for hip fracture, multivariable logistic regression analyses showed that APFF was an independent risk factor of complications following the initial management (Odds ratio 11.1, 95% confidence interval 1.05-117.2, p = 0.045). However, no significant association between PFF and APFF was observed in the patients with arthroplasty for other hip diseases. The risk of complications was higher in the APFF group than in the typical PFF group in the patients with arthroplasty for fracture. When AFPP after arthroplasty for the fracture is suspected, it may be necessary to add not only internal fixation with a normal plate but also some additional treatment.

Indexed as

AgedArthroplastyArthroplasty, Replacement, HipDiphosphonatesDisease ProgressionFemaleFemoral FracturesFracture Fixation, InternalFracture HealingHip FracturesHip ProsthesisHumansJapanMaleMiddle AgedMultivariate AnalysisDiphosphonates

Identifiers

PMID34257322
PMCPMC8277775
OpenAlexW3178175156

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.