ArticleNPJ breast cancer2021
Prediction of quality of life in early breast cancer upon completion of adjuvant chemotherapy.
Article in NPJ breast cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The quality of life assessment of breast cancer patients.Breast disease · 2024Pooled it
- Quality of life in breast cancer survivors: An ambiguous loss perspective.Journal of family theory & review · 2025Article
- Quality of Life Assessment of Breast Cancer Patients Undergoing Chemotherapy in Jordan: A Cross-Sectional Study.International journal of breast cancer · 2025Article
- Quality of Life and Its Associated Factors Among Breast Cancer Women in Iraq: A Cross-Sectional Study.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Mitochondria-based holistic 3PM approach as the 'game-changer' for individualised rehabilitation-the proof-of-principle model by treated breast cancer survivors.The EPMA journal · 2024Article
- Factors Associated with Health-Related Quality of Life Among Breast Cancer Survivors in Saudi Arabia: Cross-Sectional Study.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Can Oncologists Prompt Patient Prognostic Awareness to Enhance Decision-Making? Data From the NEOetic Study.The oncologist · 2023Article
- Prediction Model for Postoperative Quality of Life Among Breast Cancer Survivors Along the Survivorship Trajectory From Pretreatment to 5 Years: Machine Learning-Based Analysis.JMIR public health and surveillance · 2023Article
- Assessing the Quality of Life in Breast Cancer Women: A Cross Sectional Descriptive Study.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Learning in times of stress: Lessons from COVID-19 that will last throughout this century.European journal of internal medicine · 2022Article
- Prediction of quality of life in early breast cancer upon completion of adjuvant chemotherapy.NPJ breast cancer · 2021Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quality of life (QoL) is a complex, ordinal endpoint with multiple conditioning factors. A predictive model of QoL after adjuvant chemotherapy can support decision making or the communication of information about the range of treatment options available. Patients with localized breast cancer (n = 219) were prospectively recruited at 17 centers. Participants completed the EORTC QLQ-C30 questionnaire. The primary aim was to predict health status upon completion of adjuvant chemotherapy adjusted for multiple covariates. We developed a Bayesian model with six covariates (chemotherapy regimen, TNM stage, axillary lymph node dissection, perceived risk of recurrence, age, type of surgery, and baseline EORTC scores). This model allows both prediction and causal inference. The patients with mastectomy reported a discrete decline on all QoL scores. The effect of surgery depended on the interaction with age. Women with ages on either end of the range displayed worse scores, especially with mastectomy. The perceived risk of recurrence had a striking effect on health status. In conclusion, we have developed a predictive model of health status in patients with early breast cancer based on the individual's profile.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.