Evidence map›Paper›PMID 34257100›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2022

Growth in extremely preterm children born in England in 1995 and 2006: the EPICure studies.

Yanyan Ni, Rebecca Lancaster, Emmi Suonpera, Marialivia Bernardi, Amanda Fahy, Jennifer Larsen, Jayne Trickett, John R Hurst, Dieter Wolke, Samantha Johnson and 1 more

Open access · hybridAbstract read
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In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Review
  5. [Research hotspots in post-discharge follow-up management of preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
  6. Comparing autism phenotypes in children born extremely preterm and born at term.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yanyan NiEGA Institute for Women's Health, University College London, London, UK yanyan.ni.13@ucl.ac.uk.ORCID http://orcid.org/0000-0002-8745-3453
Rebecca LancasterDepartment of Health Sciences, University of Leicester, Leicester, UK.
Emmi SuonperaEGA Institute for Women's Health, University College London, London, UK.
Marialivia BernardiEGA Institute for Women's Health, University College London, London, UK.
Amanda FahyEGA Institute for Women's Health, University College London, London, UK.
Jennifer LarsenDepartment of Health Sciences, University of Leicester, Leicester, UK.
Jayne TrickettDepartment of Health Sciences, University of Leicester, Leicester, UK.
John R HurstUCL Respiratory, University College London, London, UK.
Dieter WolkeDepartment of Psychology, University of Warwick, Coventry, UK.ORCID http://orcid.org/0000-0003-0304-268X
Samantha JohnsonDepartment of Health Sciences, University of Leicester, Leicester, UK.
Neil MarlowEGA Institute for Women's Health, University College London, London, UK.ORCID http://orcid.org/0000-0001-5890-2953
University College London · GBUniversity of Leicester · GBUniversity of Warwick · GB

Funding

Medical Research Council MR/N024869/1
6 · The paper itself

Abstract

objectivesTo determine growth outcomes at 11 years of age in children born <27 weeks of gestation in England in 2006 (EPICure2) and to compare growth from birth to 11 years of age for births<26 weeks with those in England in 1995 (EPICure).

methods200 EPICure2 children assessed at 11 years alongside 143 term-born controls. Growth measures from birth to 11 years were compared for births<26 weeks between EPICure2 (n=112) and EPICure (n=176). Growth parameter z-scores were derived from 1990 UK standards.

resultsAmong EPICure2 children, mean z-scores for height and weight were close to the population standards (0.08 and 0.18 SD, respectively) but significantly below those of controls: difference in mean (Δ) z-scores for weight -0.42 SD (95% CI -0.68 to -0.17), for height -0.45 SD (-0.70 to -0.20) and for head circumference (HC) -1.05 SD (-1.35 to -0.75); mean body mass index (BMI) z-score in EPICure2 children was 0.18 SD, not significantly different from controls (0.43 SD, p=0.065). Compared with EPICure, EPICure2 children born <26 weeks at 11 years had higher z-scores for weight (Δ 0.72 (0.47, 0.96)), height (Δ 0.55 (0.29, 0.81)) and BMI (Δ 0.56 (0.24, 0.87)), which were not fully explained by perinatal/demographic differences between eras. Weight catch-up was greater from term-age to 2.5/3 years in EPICure2 than in EPICure (1.25 SD vs 0.53 SD; p<0.001). Poor HC growth was observed in EPICure2, unchanged from EPICure.

conclusionsSince 1995, childhood growth in weight, height and BMI have improved for births <26 weeks of gestation, but there was no improvement in head growth.

Indexed as

Child DevelopmentBody HeightBody Mass IndexChildChild, PreschoolEnglandFemaleFetal Growth RetardationGestational AgeGrowth DisordersHumansInfantInfant, Extremely PrematureInfant, NewbornMaleProspective Studiesgrowthneonatology

Identifiers

PMID34257100
PMCPMC8867260
OpenAlexW3178195144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.