ArticleGenome biology2021
Revealing the full biosphere structure and versatile metabolic functions in the deepest ocean sediment of the Challenger Deep.
Article in Genome biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36 citing papers in PubMed.
- Insight into the role of Sho1 in high-hydrostatic pressure and oxidative stress adaptation of the hadal fungusApplied and environmental microbiology · 2026Article
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- Carbon, nitrogen, and sulfur cycling unveil deep-sea microbial niches in the Atacama Trench.Nature communications · 2026Article
- Variations in deep-sea microbial composition and assembly mechanisms under different culture strategies.Frontiers in microbiology · 2026Article
- Clear niche partitioning of nitrite-oxidizing bacteria from the bottom and the slope of Mariana Trench.Microbiome · 2025Article
- The HOG signal pathway contributes to survival strategies of the piezo-tolerant fungusApplied and environmental microbiology · 2025Article
- Organic matter degradation by oceanic fungi differs between polar and non-polar waters.Nature communications · 2025Article
- Article
- Genomic evidence on the distribution and ecological function of Pseudomonas in hadal zone.BMC microbiology · 2025Article
- Extensive halogenated organic compound reservoirs and active microbial dehalogenation in Mariana Trench sediments.The ISME journal · 2025Article
- Diversity and ecological potentials of viruses inhabiting in the Kermadec and Diamantina trench sediments.ISME communications · 2025Article
- Alkane degradation mechanism ofFrontiers in microbiology · 2025Article
- Advances in Extremophile Research: Biotechnological Applications through Isolation and Identification Techniques.Life (Basel, Switzerland) · 2024Review
- Microbial communities reveal niche partitioning across the slope and bottom zones of the challenger deep.Environmental microbiology reports · 2024Article
- Article
- Global Marine Cold Seep Metagenomes Reveal Diversity of Taxonomy, Metabolic Function, and Natural Products.Genomics, proteomics & bioinformatics · 2024Article
- Widespread and active piezotolerant microorganisms mediate phenolic compound degradation under high hydrostatic pressure in hadal trenches.Marine life science & technology · 2024Article
- The Expanding Diversity of Viruses from Extreme Environments.International journal of molecular sciences · 2024Review
- A unique subseafloor microbiosphere in the Mariana Trench driven by episodic sedimentation.Marine life science & technology · 2024Article
- Comparative Metagenomic Analysis of Bacteriophages and Prophages in Gnotobiotic Mouse Models.Microorganisms · 2024Article
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15 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe full biosphere structure and functional exploration of the microbial communities of the Challenger Deep of the Mariana Trench, the deepest known hadal zone on Earth, lag far behind that of other marine realms.
resultsWe adopt a deep metagenomics approach to investigate the microbiome in the sediment of Challenger Deep, Mariana Trench. We construct 178 metagenome-assembled genomes (MAGs) representing 26 phyla, 16 of which are reported from hadal sediment for the first time. Based on the MAGs, we find the microbial community functions are marked by enrichment and prevalence of mixotrophy and facultative anaerobic metabolism. The microeukaryotic community is found to be dominated by six fungal groups that are characterized for the first time in hadal sediment to possess the assimilatory and dissimilatory nitrate/sulfate reduction, and hydrogen sulfide oxidation pathways. By metaviromic analysis, we reveal novel hadal Caudovirales clades, distinctive virus-host interactions, and specialized auxiliary metabolic genes for modulating hosts' nitrogen/sulfur metabolism. The hadal microbiome is further investigated by large-scale cultivation that cataloged 1070 bacterial and 19 fungal isolates from the Challenger Deep sediment, many of which are found to be new species specialized in the hadal habitat.
conclusionOur hadal MAGs and isolates increase the diversity of the Challenger Deep sediment microbial genomes and isolates present in the public. The deep metagenomics approach fills the knowledge gaps in structure and diversity of the hadal microbiome, and provides novel insight into the ecology and metabolism of eukaryotic and viral components in the deepest biosphere on earth.
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