Evidence map›Paper›PMID 34256781›Full record

ArticleWorld journal of emergency surgery : WJES2021

The negative effects of COVID-19 and national lockdown on emergency surgery morbidity due to delayed access.

Francesco A Ciarleglio, Marta Rigoni, Liliana Mereu, Cai Tommaso, Alessandro Carrara, Gianni Malossini, Saverio Tateo, Giuseppe Tirone, Truls E Bjerklund Johansen, Pier Paolo Benetollo and 5 more

Open access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Francesco A CiarleglioGeneral Surgery II & HPB Unit, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, Largo Medaglie d'Oro, 1, 38122, Trento, Italy. francesco.ciarleglio@apss.tn.it.ORCID 0000-0002-1489-1954
Marta RigoniIRCS - Innovation and Clinical Health Research - Bruno Kessler Foundation (FBK), 38123, Trento, Italy.ORCID 0000-0002-0530-9491
Liliana MereuObstetrics and Gynaecology Unit, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, 38122, Trento, Italy.ORCID 0000-0002-0610-5132
Cai TommasoUrology Unit, APSS, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, 38122, Trento, Italy.ORCID 0000-0002-7234-3526
Alessandro CarraraGeneral Surgery I & Thoracic Unit, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, 38122, Trento, Italy.ORCID 0000-0002-9508-335X
Gianni MalossiniUrology Unit, APSS, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, 38122, Trento, Italy.ORCID 0000-0001-8766-814X
Saverio TateoObstetrics and Gynaecology Unit, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, 38122, Trento, Italy.ORCID 0000-0002-5824-8020
Giuseppe TironeGeneral Surgery I & Thoracic Unit, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, 38122, Trento, Italy.
Truls E Bjerklund JohansenInstitute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID 0000-0003-3490-6460
Pier Paolo BenetolloProvincial Health Care Agency Staff Management, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, Trento, Italy.ORCID 0000-0002-2041-8194
Antonio FerroProvincial Health Care Agency Staff Management, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, Trento, Italy.
Giovanni Maria GuarreraProvincial Health Care Agency Staff Management, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, Trento, Italy.ORCID 0000-0001-9841-1972
Mario GrattarolaProvincial Health Care Agency Staff Management, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, Trento, Italy.
Giandomenico NolloIRCS - Innovation and Clinical Health Research - Bruno Kessler Foundation (FBK), 38123, Trento, Italy.ORCID 0000-0002-9837-083X
Alberto BroleseGeneral Surgery II & HPB Unit, Azienda Provinciale per i Servizi Sanitari (APSS), Santa Chiara Hospital, Largo Medaglie d'Oro, 1, 38122, Trento, Italy.ORCID 0000-0002-6362-9055
Ospedale Santa Chiara · ITUniversity of Trento · ITOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this retrospective comparative study was to assess the impact of COVID-19 and delayed emergency department access on emergency surgery outcomes, by comparing the main clinical outcomes in the period March-May 2019 (group 1) with the same period during the national COVID-19 lockdown in Italy (March-May 2020, group 2).

methodsA comparison (groups 1 versus 2) and subgroup analysis were performed between patients' demographic, medical history, surgical, clinical and management characteristics.

resultsTwo-hundred forty-six patients were included, 137 in group 1 and 109 in group 2 (p = 0.03). No significant differences were observed in the peri-operative characteristics of the two groups. A declared delay in access to hospital and preoperative SARS-CoV-2 infection rates were 15.5% and 5.8%, respectively in group 2. The overall morbidity (OR = 2.22, 95% CI 1.08-4.55, p = 0.03) and 30-day mortality (OR = 1.34, 95% CI 0.33-5.50, =0.68) were significantly higher in group 2. The delayed access cohort showed a close correlation with increased morbidity (OR = 3.19, 95% CI 0.89-11.44, p = 0.07), blood transfusion (OR = 5.13, 95% CI 1.05-25.15, p = 0.04) and 30-day mortality risk (OR = 8.00, 95% CI 1.01-63.23, p = 0.05). SARS-CoV-2-positive patients had higher risk of blood transfusion (20% vs 7.8%, p = 0.37) and ICU admissions (20% vs 2.6%, p = 0.17) and a longer median LOS (9 days vs 4 days, p = 0.11).

conclusionsThis article provides enhanced understanding of the effects of the COVID-19 pandemic on patient access to emergency surgical care. Our findings suggest that COVID-19 changed the quality of surgical care with poorer prognosis and higher morbidity rates. Delayed emergency department access and a "filter effect" induced by a fear of COVID-19 infection in the population resulted in only the most severe cases reaching the emergency department in time.

Indexed as

EmergenciesPandemicsAdultAgedCommunicable Disease ControlComorbidityCOVID-19Emergency Service, HospitalFemaleFollow-Up StudiesHospitalizationHumansItalyMaleMiddle AgedRetrospective StudiesComplicationsCOVID-19 diseaseDelayed accessEmergency surgerySurgical care

Identifiers

PMID34256781
PMCPMC8276199
OpenAlexW3180675180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.