Evidence map›Paper›PMID 34256757›Full record

ArticleMalaria journal2021

Residual malaria in Jazan region, southwestern Saudi Arabia: the situation, challenges and climatic drivers of autochthonous malaria.

Hesham M Al-Mekhlafi, Aymen M Madkhali, Khalid Y Ghailan, Ahmed A Abdulhaq, Ahmad Hassn Ghzwani, Khalid Ammash Zain, Wahib M Atroosh, Alkhansa Alshabi, Hussein A Khadashi, Majid A Darraj and 1 more

Abstract read
In one paragraph

Article in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  7. Genetic diversity and haplotype structure of theFrontiers in cellular and infection microbiology · 2025
    Article
  8. Article
  9. Women's access to healthcare services in the Jazan region of the KSA.Journal of Taibah University Medical Sciences · 2024
    Article
  10. Epidemiology and antimicrobial resistance patterns of bacterial meningitis among hospitalized patients at a tertiary care hospital in Saudi Arabia: a six-year retrospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  11. Article
  12. Spatiotemporal Distribution of Malaria in the Kingdom of Saudi Arabia.Tropical medicine and infectious disease · 2024
    Article
  13. Article
  14. Status of malaria infection in KSA during 2017-2021.Journal of Taibah University Medical Sciences · 2023
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hesham M Al-MekhlafiMedical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia. halmekhlafi@yahoo.com.ORCID http://orcid.org/0000-0003-2582-7410
Aymen M MadkhaliMedical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Khalid Y GhailanFaculty of Public Health and Tropical Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia. khalid.ghailan@gmail.com.
Ahmed A AbdulhaqDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Ahmad Hassn GhzwaniMedical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Khalid Ammash ZainMedical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Wahib M AtrooshDepartment of Parasitology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Alkhansa AlshabiDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Hussein A KhadashiMedical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Majid A DarrajDepartment of Internal Medicine, Faculty of Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.
Zaki M EisaSaudi Centre for Disease Prevention and Control, Ministry of Health, Jazan, Kingdom of Saudi Arabia.

Funding

Jazan University JUP8//000250
6 · The paper itself

Abstract

backgroundSaudi Arabia and Yemen are the only two countries in the Arabian Peninsula that are yet to achieve malaria elimination. Over the past two decades, the malaria control programme in Saudi Arabia has successfully reduced the annual number of malaria cases, with the lowest incidence rate across the country reported in 2014. This study aims to investigate the distribution of residual malaria in Jazan region and to identify potential climatic drivers of autochthonous malaria cases in the region.

methodsA cross-sectional study was carried out from 1 April 2018 to 31 January 2019 in Jazan region, southwestern Saudi Arabia, which targeted febrile individuals attending hospitals and primary healthcare centres. Participants' demographic data were collected, including age, gender, nationality, and residence. Moreover, association of climatic variables with the monthly autochthonous malaria cases reported during the period of 2010-2017 was retrospectively analysed.

resultsA total of 1124 febrile subjects were found to be positive for malaria during the study period. Among them, 94.3 and 5.7% were infected with Plasmodium falciparum and Plasmodium vivax, respectively. In general, subjects aged 18-30 years and those aged over 50 years had the highest (42.7%) and lowest (5.9%) percentages of malaria cases. Similarly, the percentage of malaria-positive cases was higher among males than females (86.2 vs 13.8%), among non-Saudi compared to Saudi subjects (70.6 vs 29.4%), and among patients residing in rural rather than in urban areas (89.8 vs 10.2%). A total of 407 autochthonous malaria cases were reported in Jazan region between 2010 and 2017. Results of zero-inflated negative binomial regression analysis showed that monthly average temperature and relative humidity were the significant climatic determinants of autochthonous malaria in the region.

conclusionMalaria remains a public health problem in most governorates of Jazan region. The identification and monitoring of malaria transmission hotspots and predictors would enable control efforts to be intensified and focused on specific areas and therefore expedite the elimination of residual malaria from the whole region.

Indexed as

ClimateWeatherAdolescentAdultAgedAged, 80 and overChildChild, PreschoolEndemic DiseasesFemaleHumansIncidenceInfantInfant, NewbornMalaria, FalciparumMalaria, VivaxClimatic factorsEliminationInfectious diseasesJazanMalariaSaudi Arabia

Identifiers

PMID34256757
PMCPMC8276496

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.