ArticleGenetics, selection, evolution : GSE2021
Selection for environmental variance of litter size in rabbits involves genes in pathways controlling animal resilience.
Article in Genetics, selection, evolution : GSE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Capturing resilience from phenotypic deviations: a case study using feed consumption and whole genome data in pigs.BMC genomics · 2024Article
- A first characterization of the microbiota-resilience link in swine.Microbiome · 2024Article
- Selection for environmental variance shifted the gut microbiome composition driving animal resilience.Microbiome · 2023Article
- Breed identification using breed-informative SNPs and machine learning based on whole genome sequence data and SNP chip data.Journal of animal science and biotechnology · 2023Article
- Effect of environmental variance-based resilience selection on the gut metabolome of rabbits.Genetics, selection, evolution : GSE · 2023Article
- Comparative analysis of genomic inbreeding parameters and runs of homozygosity islands in several fancy and meat rabbit breeds.Animal genetics · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundEnvironmental variance (V
resultsBy combining signatures of selection and WGS data, we detected 373 genes with functional mutations in their transcription units, among which 111 had functions related to the immune system, stress response, reproduction and embryo development, and/or carbohydrate and lipid metabolism. The genes TTC23L, FBXL20, GHDC, ENSOCUG00000031631, SLC18A1, CD300LG, MC2R, and ENSOCUG00000006264 were particularly relevant, since each one carried a functional mutation that was fixed in one of the rabbit lines and absent in the other line. In the 3'UTR region of the MC2R and ENSOCUG00000006264 genes, we detected a novel insertion/deletion (INDEL) variant.
conclusionsOur findings provide further evidence in favour of V
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.