Evidence map›Paper›PMID 34256352›Full record

ReviewCurrent opinion in virology2021

Animal models of SARS-CoV-2 transmission.

Rory D de Vries, Barry Rockx, Bart L Haagmans, Sander Herfst, Marion Pg Koopmans, Rik L de Swart

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rory D de VriesDepartment Viroscience, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Barry RockxDepartment Viroscience, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Bart L HaagmansDepartment Viroscience, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Sander HerfstDepartment Viroscience, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Marion Pg KoopmansDepartment Viroscience, Erasmus MC, University Medical Center Rotterdam, The Netherlands.
Rik L de SwartDepartment Viroscience, Erasmus MC, University Medical Center Rotterdam, The Netherlands. Electronic address: r.deswart@erasmusmc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 emerged in China as a zoonotic virus in December 2019. The virus proved to be human-to-human transmissible and its global spread resulted in the ongoing COVID-19 pandemic, associated with high morbidity and mortality. Vaccines were developed at an unprecedented speed and proved to be efficacious in preventing disease, but it remains to be determined if vaccines are able to interrupt transmission. Moreover, virus variants of concern continue to emerge that appear more transmissible and/or less sensitive to virus-specific immune responses. Here, we briefly review the role of animal models in assessing prophylactic and therapeutic options to interrupt SARS-CoV-2 transmission.

Indexed as

Disease Models, AnimalSARS-CoV-2AnimalsCOVID-19CricetinaeHumans

Identifiers

PMID34256352
PMCPMC8238653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.