Evidence map›Paper›PMID 34255730›Full record

ArticleAJNR. American journal of neuroradiology2021

CT Cervical Spine Fracture Detection Using a Convolutional Neural Network.

J E Small, P Osler, A B Paul, M Kunst

Abstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. IShuffleNet-PCNN hybrid classifier within an MResU-Net-based framework for spinal cord injury detection and classification using CT images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. A two-stage deep learning system for cervical spine fracture diagnosis: integrating 3D segmentation and 2.5D classification on CT images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. ShuffleLeNet architecture for spinal cord injury classification and level detection.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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  8. Spinal Cord Segmentation and Injury Detection based on Siamese Conventional WideRes Network using CT Image.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

J E SmallFrom the Departments of Neuroradiology (J.E.S., A.B.P., M.K.) Juan.E.Small@Lahey.org.ORCID 0000-0002-4931-3564
P OslerRadiology (P.O), Lahey Hospital and Medical Center, Burlington, Massachusetts.ORCID 0000-0003-4883-2925
A B PaulFrom the Departments of Neuroradiology (J.E.S., A.B.P., M.K.).ORCID 0000-0002-5579-9855
M KunstFrom the Departments of Neuroradiology (J.E.S., A.B.P., M.K.).ORCID 0000-0002-7104-0101

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeMultidetector CT has emerged as the standard of care imaging technique to evaluate cervical spine trauma. Our aim was to evaluate the performance of a convolutional neural network in the detection of cervical spine fractures on CT. MATERIALS AND

methodsWe evaluated C-spine, an FDA-approved convolutional neural network developed by Aidoc to detect cervical spine fractures on CT. A total of 665 examinations were included in our analysis. Ground truth was established by retrospective visualization of a fracture on CT by using all available CT, MR imaging, and convolutional neural network output information. The ĸ coefficients, sensitivity, specificity, and positive and negative predictive values were calculated with 95% CIs comparing diagnostic accuracy and agreement of the convolutional neural network and radiologist ratings, respectively, compared with ground truth.

resultsConvolutional neural network accuracy in cervical spine fracture detection was 92% (95% CI, 90%-94%), with 76% (95% CI, 68%-83%) sensitivity and 97% (95% CI, 95%-98%) specificity. The radiologist accuracy was 95% (95% CI, 94%-97%), with 93% (95% CI, 88%-97%) sensitivity and 96% (95% CI, 94%-98%) specificity. Fractures missed by the convolutional neural network and by radiologists were similar by level and location and included fractured anterior osteophytes, transverse processes, and spinous processes, as well as lower cervical spine fractures that are often obscured by CT beam attenuation.

conclusionsThe convolutional neural network holds promise at both worklist prioritization and assisting radiologists in cervical spine fracture detection on CT. Understanding the strengths and weaknesses of the convolutional neural network is essential before its successful incorporation into clinical practice. Further refinements in sensitivity will improve convolutional neural network diagnostic utility.

Indexed as

Spinal FracturesCervical VertebraeHumansNeural Networks, ComputerRetrospective StudiesSensitivity and SpecificityTomography, X-Ray Computed

Identifiers

PMID34255730
PMCPMC8324280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.